Results 31 to 40 of about 505,676 (266)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Evaluation of rational energy costs for liquid dispersion in piston compressors with a two-phase working fluid [PDF]

Омский научный вестник: Серия "Авиационно-ракетное и энергетическое машиностроение"
The paper considers the condition of efficient operation of a piston compressor with coolant injection, which consists in the fact that the costs of its spraying and injection should be less than the gain in indicator work obtained with intensive gas ...
V. E. Scherba, A. K. Kuzhbanov, M. I. Gildebrandt, V. Yu. Kudentsov, N. S. Galdin, A. A. Gladenko   +5 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

LABORATORY INVESTIGATION OF THE PERFORMANCE OF TWO-COMPONENT GROUT BEHIND THE SEGMENT IN SANDY SOILS BELOW THE WATER TABLE LEVEL

Rudarsko-geološko-naftni Zbornik
The increasing use of TBMs in urban areas has heightened the significance of grouting behind tunnel segments. A key aspect of mechanized tunnelling is the application of grout for injection behind the tunnel segments (support system) to prevent ground ...
Samaneh Khodaei, Erfan Khoshzaher, Hamid Chakeri, Shahla Miri Darmarani   +3 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Performance–Emission Trade‐Offs in RCCI Engines Using High‐Viscosity Alcohol–Diesel Blends Under Variable Injection Pressures

Engineering Reports
This study experimentally investigates the performance, combustion, and emission characteristics of a Reactivity‐Controlled Compression Ignition (RCCI) engine fueled with diesel and the high‐viscosity oxygenated alcohol 2‐Methyl‐1‐butanol.
S. M. Ferdous Azam, Dipak Patel, Ripendeep Singh, Sikata Samantaray, Aravindan M. K., Nivin Joy Thykattusserry, Jasgurpreet Singh Chohan, Yashwant Singh Bisht, Abhijit Bhowmik, Yalew Tamene   +9 more
doaj   +1 more source

Injection and Combustion Analysis of Pure Rapeseed Oil Methyl Ester (RME) in a Pump-Line-Nozzle Fuel Injection System

Energies, 2021
This work suggests an interpretation to the quantitatively higher formation of NOx in a compression ignition (CI) engine when fueled with pure biodiesel (B100). A comparative study about the use of rapeseed oil methyl ester (RME) and diesel fuel mixtures
Flavio Caresana, Marco Bietresato, Massimiliano Renzi   +2 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source