Results 101 to 110 of about 2,025,323 (287)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Burning rate control of solid propellants Patent [PDF]

, 1967
Pressurized gas injection for burning rate control of solid ...
Heidmann, M. F., Povinelli, L. A.
core   +1 more source

Cold gas in the Intra Cluster Medium: implications for flow dynamics and powering optical nebulae

, 2008
We show that the mechanical energy injection rate generated as the intra-cluster medium (ICM) flows around cold clouds may be sufficient to power the optical and near infra-red emission of nebulae observed in the central regions of a sample of seven ...
Boehringer, Bîrzan, Crawford, Crawford, Crowe, Daines, Donahue, Donahue, Edge, Edward C. D. Pope, Ferland, Field, Hatch, Hatch, Heckman, Heckman, Henderson, Jaffe, Jaffe, Jaffe, Jaffe, Johnstone, Julian M. Pittard, Loewenstein, McKee, Peterson, Pittard, Pope, Pope, Ruszkowski, Salomé, Salomé, Simionescu, Thomas W. Hartquist   +33 more
core   +1 more source

Correlation Between Intravascular Injection Rate, Pain Intensity, and Degree of Cervical Neural Foraminal Stenosis During a Cervical Transforaminal Epidural Block. [PDF]

J Pain Res, 2021
Kim J, Kim K, Lee M, Kim S.
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Effects of Remimazolam Dose and Bolus Injection Rate on Hiccups During Painless Colonoscopy: A Double-Blind Randomized Clinical Trial

Drug Design, Development and Therapy
Yanping Lu,1 Xuewei Wang,2 Henjing Zou,1 Changhui Shao,1 Guangyi Lai,1 Shan Ou1 1Department of Anesthesiology, Chengdu Integrated TCM & Western Medicine Hospital, Chengdu, 610000, People’s Republic of China; 2Department of Emergency, Chengdu Second ...
Lu Y, Wang X, Zou H, Shao C, Lai G, Ou S
doaj  

Experiment of complex flow in full size horizontal wells with perforated completion

Petroleum Exploration and Development, 2013
A full size perforated casing of 139.7 mm in external diameter was adopted to simulate the horizontal wellbore. The influences of perforation parameters and injection rate on the pressure drop in horizontal wells were investigated by experiments.
Jianguang WEI, Xiaoqiu WANG, Haibo CHEN, Quan ZHANG   +3 more
doaj   +1 more source

Injection rate of contrast medium affects diagnostic ability of dynamic contrast-enhanced magnetic resonance imaging for endometrial carcinoma: a prospective cohort study. [PDF]

Gland Surg, 2021
Xu D, Jin A, Ge Y, Zhang Y.
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Study on profile control ability of polymer microspheres to heterogeneous formation

Youqicang pingjia yu kaifa, 2019
The morphology and rheological properties of polymer microspheres PM1 were evaluated by optical microscope and rheometer. The effects of injection rate and concentration of microsphere system on the migration and plugging properties in porous media as ...
ZHAO Shuai, PU Wanfen, LI Kexing, YANG Yang   +3 more
doaj