Results 81 to 90 of about 2,025,323 (287)

Filter Cleaning Using Gas Injection [PDF]

open access: yes, 1995
A filter cleaning process using gas injection is considered. An estimate for the minimum mass flow rate out of the gas injector and the corresponding injector/filter geometry is found. The estimates are based on a similarity solution for a free turbulent
Hurwitz, M.F.   +3 more
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Skin friction reduction by slot injection at Mach 0.8 [PDF]

open access: yes
Surface skin friction, boundary layer profiles and turbulent intensity due to axially symmetric tangential slot injection into a transonic boundary layer were measured.
Wang, C. R., Zakkay, V.
core   +1 more source

Droplets nucleation, and Smoluchowski's equation with growth and injection of particles

open access: yes, 1997
We show that models for homogeneous and heterogeneous nucleation of D-dimensional droplets in a d-dimensional medium are described in mean-field by a modified Smoluchowski equation for the distribution N(s,t) of droplets masses s, with additional terms ...
Cueille, Stephane, Sire, Clement
core   +3 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

The Effect of Injection-Valve Opening Pressure on Spray-Tip Penetration [PDF]

open access: yes
The effect of various injection-valve opening pressures on the spray-tip penetration was determined for several injection pressure. A common-rail fuel injection system was used.
Marsh, E T, Rothrock, A M
core   +1 more source

Fluctuations of energy injection rate in a shear flow

open access: yes, 2003
We study the instantaneous and local energy injection in a turbulent shear flow driven by volume forces. The energy injection can be both positive and negative. Extremal events are related to coherent streaks.
Aumaı̂tre   +19 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Investigation on an Injection Strategy Optimization for Diesel Engines Using a One-Dimensional Spray Model

open access: yesEnergies, 2019
Common rail systems have been widely used in diesel engines due to the stricter emission regulations. The advances in injector technology and ultrahigh injection pressure greatly promote the development of multiple-injection strategy, leading to the ...
Intarat Naruemon   +3 more
doaj   +1 more source

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