Results 71 to 80 of about 1,099,154 (258)

Numerical Modeling of Variable Fluid Injection-Rate Modes on Fracturing Network Evolution in Naturally Fractured Formations

open access: yesEnergies, 2016
In this study, variable injection-rate technology was numerically investigated in a pre-existing discrete fracture network (DFN) formation, the Tarim Basin in China.
Yu Wang, Xiao Li, Bo Zhang
doaj   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Numerical Simulation of the Simultaneous Development of Multiple Fractures in Horizontal Wells Based on the Extended Finite Element Method

open access: yesEnergies
Simultaneous multiple-fracture treatments in horizontal wellbores have become an essential technology for the economic development of shale gas reservoirs. During hydraulic fracturing, fracture initiation and propagation always induce additional stresses
Enshun Ping   +6 more
doaj   +1 more source

Injection Rate Interval in Fluctuation Section of Curtain Grouting in Pumped Storage Projects [PDF]

open access: yes长江科学院院报
[Objective] Curtain grouting is a commonly used method for anti-seepage reinforcement in pumped storage projects, and injection rate is an important monitoring parameter that directly affects grouting quality. The fluctuation section of injection rate is
LIU Jie-yuan, ZHANG Fan, ZHAN Cheng-yuan, HE Ji, LIU Quan, ZHANG Hong-wei
doaj   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Effect of Liquid Injection Arrangements on Injection Flow Rate of a Laboratory-Scale Venturi Scrubber

open access: yesFrontiers in Energy Research, 2019
As the core device of a filtered containment venting system (FCVS), Venturi Scrubber is an efficient device to scrub the radioactive gases and aerosols before release into the atmosphere.
Guangzong Zheng   +5 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Experiment of complex flow in full size horizontal wells with perforated completion

open access: yesPetroleum Exploration and Development, 2013
A full size perforated casing of 139.7 mm in external diameter was adopted to simulate the horizontal wellbore. The influences of perforation parameters and injection rate on the pressure drop in horizontal wells were investigated by experiments.
Jianguang WEI   +3 more
doaj   +1 more source

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