Results 71 to 80 of about 2,025,323 (287)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
A Model for Tracking Fronts of Stress-Induced Permeability Enhancement
, 2013 Using an analogy to the classical Stefan problem, we construct evolution equations for the fluid pore pressure on both sides of a propagating stress-induced damage front.
Karra, Satish +2 more
core +1 more source
On the Robustness of Rating Aggregators Against Injection Attacks
, 2020 For a decade now, Academia has been researching refined techniques to detect fake reviews. In this article, rather than proposing a new detection methodology, we propose to contain the consequences of an attack launched by a fake reviewer who attaches arbitrary scores to the review target.
Spognardi Angelo, Petrocchi Marinella
openaire +2 more sources
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Combustion and Emission Characteristics of a Diesel Engine with a Variable Injection Rate
Applied SciencesDiesel engine combustion is dependent mainly on the fuel injection characteristics, particularly the injection pressure and rate, which directly affect the engine efficiency and emissions.
Jun Chen +7 more
doaj +1 more source
Evaluation of miscible and immiscible CO2 injection in one of the Iranian oil fields
Egyptian Journal of Petroleum, 2014 Carbon dioxide (CO2) flooding is one of the most important methods for enhanced oil recovery (EOR) because it not only increases oil recovery efficiency but also causes a reduction of greenhouse gas emissions. It is a very complex system, involving phase
Aref Hashemi Fath +1 more
doaj +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
JGEET: Journal of Geoscience, Engineering, Environment and TechnologyThe MJ well is one of the oldest in the Central Sumatra field. This field was originally produced in 1952, with a reserve of 4.5 MMSTB. This explains why EOR studies are needed to increase the production of oil.
Gaspar Fonseca Oliveira +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Applied SciencesThis study analyzes the injection behavior of fossil and sustainable aviation fuel blends, in comparison with conventional diesel fuel, using a common-rail injection system applied to reciprocating engines.
Samuel González-Ruíz +5 more
doaj +1 more source