Results 61 to 70 of about 15,316,992 (300)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Injection of Chemicals Into Irrigation Systems: Rates, Volumes, and Injection Periods

open access: yesEDIS, 1998
Irrigation systems play a crucial role in delivering soluble chemicals to crops through a process known as chemigation. This method allows for precise application of chemicals to either the root zone or aerial parts of plants, or both. Specialized equipment is required for chemigation, with various injection methods available.
Gary A. Clark   +2 more
openaire   +3 more sources

Seismicity Induced by Simultaneous Abrupt Changes of Injection Rate and Well Pressure in Hutubi Gas Field

open access: yesJournal of Geophysical Research: Solid Earth, 2018
Hutubi gas field, the largest gas storage field in China, has been operated on annual injection/extraction cycles since 9 June 2013. We study the seismicity near the gas field from 9 June 2013 to 22 October 2015, a time span that the gas field has ...
Lanlan Tang   +4 more
semanticscholar   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

On the Robustness of Rating Aggregators Against Injection Attacks

open access: yes, 2020
For a decade now, Academia has been researching refined techniques to detect fake reviews. In this article, rather than proposing a new detection methodology, we propose to contain the consequences of an attack launched by a fake reviewer who attaches arbitrary scores to the review target.
Spognardi Angelo, Petrocchi Marinella
openaire   +2 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Combustion and Emission Characteristics of a Diesel Engine with a Variable Injection Rate

open access: yesApplied Sciences
Diesel engine combustion is dependent mainly on the fuel injection characteristics, particularly the injection pressure and rate, which directly affect the engine efficiency and emissions.
Jun Chen   +7 more
doaj   +1 more source

Evaluation of miscible and immiscible CO2 injection in one of the Iranian oil fields

open access: yesEgyptian Journal of Petroleum, 2014
Carbon dioxide (CO2) flooding is one of the most important methods for enhanced oil recovery (EOR) because it not only increases oil recovery efficiency but also causes a reduction of greenhouse gas emissions. It is a very complex system, involving phase
Aref Hashemi Fath   +1 more
doaj   +1 more source

Concurrent Treatment With Lorlatinib and Dinutuximab Beta Induced Acute Gastric Dilation in a Pediatric Patient With Neuroblastoma

open access: yes
Pediatric Blood &Cancer, EarlyView.
Suna Lin   +6 more
wiley   +1 more source

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