Results 51 to 60 of about 1,138,447 (216)

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Relationship Between Spinal Anesthesia Injection Speed and the Incidence of Hypotension in Patients Undergoing Cesarean Section

open access: yesSolo Journal of Anesthesi, Pain and Critical Care
Background : The incidence of post-spinal hypotension in pregnancy is very high 50-85%. There have been many studies preventing hypotension but still considered unsatisfactory.
Fikri Alim Mafazi   +2 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

OPTIMIZATION OF THE FORMATION ACID FRACTURING AT THE FACILITIES OF OJSC «TATNEFT»

open access: yesИзвестия высших учебных заведений: Нефть и газ, 2015
The authors analyzed the process parameters of the formation acid hydraulic fracturing (FAHF) operations performing taking into account the additional production achieved.
I. I. Mannanov, L. I. Garipova
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Sensor for Injection Rate Measurements

open access: yesSensors, 2006
A vast majority of the medium and high speed Diesel engines are equipped withmulti-hole injection nozzles nowadays. Inaccuracies in workmanship and changinghydraulic conditions in the nozzles result in differences in injection rates between ...
Milan Marcic
doaj   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

An Analysis on the Effects of the Fuel Injection Rate Shape of the Diesel Spray Mixing Process Using a Numerical Simulation

open access: yesApplied Sciences, 2020
In diesel engines, fuel mixing is an important process in determining the combustion efficiency and emissions level. One of the measures used to achieve fuel mixing is controlling the nature and behavior of the fuel spray by shaping the injection rate ...
Intarat Naruemon   +4 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

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