Results 121 to 130 of about 20,589 (216)

High‐altitude headache: Insights into pathophysiology and potential treatment implications

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude headache occurs during prolonged exposure to low oxygen, such as during ascent to high altitude. Several risk factors increase its likelihood, with the degree of hypoxia, often driven by rapid ascent to greater altitudes, being the most prominent factor.
Marika Falla   +3 more
wiley   +1 more source

Mitochondrial physiology in cardiac muscle of deer mice native to high altitude

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude deer mice exhibited evolved changes in mitochondrial energy metabolism and reactive oxygen species (ROS) management that may support cardiac performance under cold hypoxic conditions. High‐altitude mice had increased activity of lactate dehydrogenase (LDH) in the heart, probably enhancing the capacity for lactate ...
Ranim Saleem   +3 more
wiley   +1 more source

The role of group III/IV afferent feedback in the ventilatory, pressor and metabolic responses to exercise in normoxia and hypoxia

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Participants completed cycling exercise with (placebo) and without (25 µg intrathecal fentanyl) intact group III/IV muscle afferent feedback in three settings: normoxia, acute hypoxia and chronic hypoxia after 7–9 days of acclimatisation (∼3800 m). Blocking afferent feedback suppressed exercise hyperpnoea across all environments,
Elliott J. Jenkins   +23 more
wiley   +1 more source

Intra‐abdominal pressure and intestinal microbiome are associated with clinical outcomes in sepsis patients receiving early enteral nutrition: A prospective observational study

open access: yesHong Kong Journal of Emergency Medicine, Volume 33, Issue 4, August 2026.
Abstract Introduction Intra‐abdominal pressure (IAP) and gut microbiota have been associated with the prognosis of patients with sepsis receiving early enteral nutrition (EEN). In this study, we investigated this association and its prognostic value. Methods In this prospective observational study, we enrolled patients with sepsis receiving EEN.
Kaihui Zheng   +9 more
wiley   +1 more source

Safety and Efficacy of Mesenchymal Stem Cell Therapy in Multiple System Atrophy: Systematic Review. [PDF]

open access: yesBiologics
Elimam N   +7 more
europepmc   +1 more source

Quantitative Imaging of Pyruvate Metabolism in a Patient With Anaplastic Thyroid Cancer

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 2, Page 826-838, August 2026.
ABSTRACT Purpose Magnetic resonance imaging using hyperpolarized (HP) [1‐13C]‐pyruvate enables assessment of pyruvate metabolism in vivo and offers new insight into metabolic changes in response to cancer therapy. Widely used semi‐quantitative metrics of pyruvate metabolism can be affected by physiological factors that are extrinsic to intracellular ...
James A. Bankson   +18 more
wiley   +1 more source

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