Results 131 to 140 of about 26,232 (250)

Mesenchymal stromal cell therapy for rheumatoid arthritis: Long‐term efficacy, safety, and mechanistic insights

Rheumatology &Autoimmunity, EarlyView.
Graphical abstract summarizing the multifactorial pathogenesis of rheumatoid arthritis (RA) and the therapeutic potential of mesenchymal stromal cell (MSC) therapy. MSCs provide promising benefits through their immunomodulatory properties, low immunogenicity, ability to promote tissue repair, and multi‐lineage differentiation, presenting a potential ...
Yingjia Chen, Ruiyu Gao, Xing Guo, Genhong Yao, Xiaojun Tang, Yile E. Liu, Lingyun Sun   +6 more
wiley   +1 more source

Physician Responses to a Subsidy Removal: The Case of Joint Injections Under Australia's Medicare Program

Economic Record, EarlyView.
This study examines the effects of a public subsidy withdrawal on provider behaviour, focusing on General Practitioners (GPs) in Australia. Specifically, it explores changes in GP billing practices following the removal of an item on the Medicare Benefits Schedule that subsidises joint injections (intra‐articular steroids).
Olukorede Abiona, Maryam Naghsh‐Nejad, Kees Van Gool, Phil Haywood, Jane Hall   +4 more
wiley   +1 more source

Hypersensitivity to Excipients in Drugs: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Drugs contain active pharmaceutical ingredients and excipients, compounds which enhance the pharmacokinetics, stability and palatability of the pharmaceutical formulation. While most drug hypersensitivity reactions (DHR) are caused by active ingredients, excipients may also be involved.
Lene H. Garvey, Knut Brockow, Annick Barbaud, Charlotte G. Mortz, Gianfranco Calogiuri, Asli Gelincik, Osman O. Yeğit, Alla Nakonechna, Annette Wagner, Rik Schrijvers, Toon Ieven   +10 more
wiley   +1 more source

Comparison of Different Molecular Weights of Intra-Articular Hyaluronic Acid Injections for Knee Osteoarthritis: A Level I Bayesian Network Meta-Analysis

Background: The present Bayesian network meta-analysis compared the efficacy of intra-articular injections of different molecular weights of hyaluronic acid (HA) in patients with knee osteoarthritis.
Maffulli, Nicola, Pappalardo, Gaetano, Kubach, Joshua, Migliorini, Filippo, Nijboer, Cornelis Hindriks, Pasurka, Mario, Betsch, Marcel   +6 more
core   +1 more source

Platelet-rich plasma intra-articular injections in reducing pain and improving function in patients with osteoarthritis

, 2020
Whether the complex and time-intensive requirements for administering PRP warrants its use for intra-articular (IA) therapy in OA is in question and should be examined. If PRP is at least or even more effective than corticosteroids or hyaluronic acid (HA)
Brekke, Chelsea M.
core  

PO:09:134 | The impact of intra-articular hyaluronic acid injections on osteoarthritis synovitis: a study on synovial tissue of total knee arthroplasty patients

Reumatismo
Background. Intra-articular hyaluronic acid injections (IA-HA) represent a therapeutic strategy widely used to manage knee osteoarthritis, aiming to reduce pain and to improve joints’ range of movement.
Società Italiana di Reumatologia
doaj  

Musculoskeletal health among adults with cerebral palsy: A systematic review

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To describe the burden of, and investigate prognostic factors for, osteoarthritis, osteopenia and/or osteoporosis, spondylosis, and fracture, and to investigate the effectiveness of protocols for monitoring musculoskeletal disorders and interventions for managing osteoarthritis in adults with cerebral palsy (CP).
Jennifer M. Ryan, Jessica Burke, Rachel Byrne, Emily Capellari, Christina M Marciniak, Maram Sofiany, Reuel Jalal, Mark Peterson, The Adult CP Clinical Practice Guideline Working Group, Jan Willem Gorter, Ashley Harris Whaley, Christine Imms   +11 more
wiley   +1 more source

Updates on intra‐articular corticosteroid administration in horses

Equine Veterinary Education, EarlyView.
Summary Intra‐articular (IA) corticosteroid administration in equine athletes has gained increased attention recently, particularly in racing. Despite widespread corticosteroid use in equine practice for decades, there are still a lack of equine‐specific studies to address key questions related to their use.
K. Tanner, L. Bass, C. Kawcak, L. V. Schnabel, K. L. Hallowell, L. M. Pezzanite   +5 more
wiley   +1 more source

Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health

The FEBS Journal, EarlyView.
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin, Sumit Bhutada, Suneel S. Apte   +2 more
wiley   +1 more source

Multiple External Invasive Root Resorption and Calcification in Systemic Sclerosis—Case Report

International Endodontic Journal, EarlyView.
ABSTRACT Aim There are few reports in the literature of multiple external invasive root resorption (EIRR) lesions in patients with systemic sclerosis (SSc), and an association between root resorption and SSc is not well established. We report the only case that comprehensively illustrates—with the combination of histopathology, cone beam computed ...
Jee‐Yun Leung, Geoffrey Heithersay, Richard Logan, Sharon Liberali   +3 more
wiley   +1 more source