Results 141 to 150 of about 26,569 (289)
Alternate Light Source (ALS) Detection Does Not Confirm Occult Bruises
Visible light spectrum. ABSTRACT Almost all victims of assault and strangulation who seek medical care receive their initial medical care in the emergency department (ED), and many patients are referred to forensic nurses during or immediately after the ED evaluation.
William Hauda II +5 more
wiley +1 more source
Induction of IL‐9‐producing CD8+ T cells by ascochlorin derivatives
A newly synthesised ascochlorin derivative, N184, induces small amounts of IL‐9‐producing CD8+ T cells. N184 improved the survival of CD8+ T cells and enhanced their antitumour activity, partially in an IL‐9‐dependent manner. The antitumour effect was completely dependent on IFNγ secretion rather than the cytotoxic activity of CD8+ T cells.
Natsumi Imano +5 more
wiley +1 more source
TEAD1 Enhances Exosome Secretion and Promotes Exosome‐Mediated Tissue Regeneration
TEAD1 functions as a crucial molecular switch regulating exosome secretion in various cell types. TEAD1 enhances exosome secretion by upregulating key proteins associated with exosome secretion, including RAB11, CD9, and SNAP23. This study reveals a novel role for TEAD1 in regulating exosome secretion and tissue regeneration, particularly in diabetic ...
Yan Pu +9 more
wiley +1 more source
Vitiligo – New Treatment Approach
Veronika A Konstantinova,1 Olga Yu Olisova,2 Victor V Gladko,3 Ekaterina P Burova2–4 1Dermatology and Cosmetology Department Dao Clinic, Leninskiy Prospekt, Moscow 119119, Russia; 2Rakhmanov Department of Dermatology and Venereal Diseases, I.M ...
Konstantinova VA +3 more
doaj
We established patient‐derived SWN cell lines and orthotopic PDX models that recapitulate patient pain phenotypes, alongside a novel intravital DRG imaging platform to track macrophage infiltration and neuronal pain responses. Using these models, we define HMGB1–CCL2–IL‐6 signaling crosstalk driving pain and identify EGF signaling as a key regulator of
Zhenzhen Yin +17 more
wiley +1 more source
Promotion of DFU Wound Healing via BRG1–COL16A1 Axis in Fibroblasts
In normal wound healing, transcription factor BRG1 is upregulated and binds the COL16A1 promoter to enhance its expression, promoting fibroblast proliferation, migration, contraction, extracellular matrix deposition, and granulation tissue formation, thus accelerating wound closure.
Penghui Wang +10 more
wiley +1 more source
The combined, intradermal application of multiple vaccines against key diseases in swine offers many benefits, including reduced time and labor costs, and improved animal welfare due to fewer injections and manipulations.
Basav N. Hangalapura +3 more
doaj +1 more source
ABSTRACT Extracellular vesicles (EVs) are nanoscale mediators of intercellular communication with diverse molecular cargoes that reflect their cell of origin. Advances in isolation, detection, and single‐particle analytics have revealed increasing molecular and functional heterogeneity, while exposing limitations in how EV identity and activity are ...
David J. Lundy +8 more
wiley +1 more source
Despite significant advances, most academic research fails to result in medical products that benefit patients. This guide shares five key steps to help researchers close that gap: set clear goals, test thoroughly, protect ideas, build diverse teams, and partner with industry.
Cristina Oldani +4 more
wiley +1 more source
ABSTRACT Background Hyaluronic acid (HA) and Botulinum toxin A (BTX‐A) treatments are highly regarded for their effectiveness in facial rejuvenation. Aim To investigate whether adding Profhilo enhances the effects of BTX‐A for frontal skin rejuvenation.
Zahra Saffarian +9 more
wiley +1 more source

