Results 131 to 140 of about 153,401 (288)
Bile acids promote lipopolysaccharide clearance via the hepato-biliary pathway in broiler chickens
Lipopolysaccharide (LPS) acts as a trigger that disrupts metabolic functions and the immune system. While bile acids (BA) have detoxification and anti-inflammatory effects, their role in promoting LPS excretion in broiler chickens remains unclear.
Liang Chen+3 more
doaj
Aims We investigated the effects of intraperitoneal injections of titanium dioxide nanoparticles (TiO2 NPs, 100 mg/kg) for 5 consecutive days on the developmental competence of murine oocytes. Furthermore, study the effects of TiO2 NPs on antioxidant and
Mohammed A Elmetwally+12 more
doaj +1 more source
THE PATHOLOGY OF INTRAPERITONEAL BILE INJECTIONS IN THE RABBIT [PDF]
C. H. Bunting, Wade H. Brown
openaire +3 more sources
Exosome‐based nanoparticles (GC‐Exo‐CD16Ab) are designed to deliver glucocorticoids (GC) specifically to decidual CD16+ NK cells and macrophages. This targeted delivery effectively suppresses the cytotoxicity of decidual NK cells, inhibits M1 macrophage polarization, and modulates the decidual microenvironment.
Linlin Wang+17 more
wiley +1 more source
Hazem Mohamed Saleh,1 Omar A Soliman,2 Mohamed Osama Elshazly,3 Alaa Raafat,2 Adel K Gohar,2 Taher A Salaheldin41Otolaryngology Unit, Department of Medical Applications, The National Institute of Laser Enhanced Sciences, Cairo University, 2Department of ...
Saleh HM+5 more
doaj
Errors in the technique of intraperitoneal injection of mice [PDF]
E P Ornellas+3 more
openaire +3 more sources
Stress Promotes Drug Seeking Through Glucocorticoid-Dependent Endocannabinoid Mobilization in the Prelimbic Cortex [PDF]
Background Clinical reports suggest that rather than directly driving cocaine use, stress may create a biological context within which other triggers for drug use become more potent. We hypothesize that stress-induced increases in corticosterone “set the
Baker, David A.+10 more
core +1 more source
Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao+14 more
wiley +1 more source
A type of polydopamine (PDA) nanogel decorated adhesive and responsive hierarchical microcarriers for ALA delivery and deafness prevention. PDA@microcarriers can protect the encapsulated drugs from external disturbances and prolong their retention time in the inner ear.
Hong Chen+8 more
wiley +1 more source
Pinoresinol diglucoside, a bioactive component extracted from traditional Chinese medicine, attenuates cisplatin‐induced ototoxicity in vivo and in vitro. The protective effect is achieved by downregulation of Socs1. The present study is the first to investigate the expression and function of Socs1 in inner ear, which is known to promote ferroptosis ...
Yin Chen+12 more
wiley +1 more source