Results 201 to 210 of about 153,401 (288)
Advanced Science, EarlyView.This study develops TMEclassifier, a machine‐learning tool that classifies cancers into three distinct subtypes—Immune exclusive (IE), immune suppressive (IS), and immune activated (IA)—which exhibit significant heterogeneity and necessitate customized therapeutic strategies.
Dongqiang Zeng +27 more
wiley +1 more source
Advances in technical methods and applications of subretinal injections in experimental animals. [PDF]
Front Vet SciSong C, Ji Y, Wang Y, Yang W.
europepmc +1 more source
Advanced Science, EarlyView.This review compares clinical outcomes, translational progress, and global funding trends across cancer phototherapies—photodynamic, photothermal, and photoimmunotherapy—and conventional immunotherapy. It highlights differences in treatment efficacy, clinical trial status, financial investment, and regulatory challenges, providing a comprehensive ...
Deepak S. Chauhan +6 more
wiley +1 more source
A Single Intraperitoneal Secreted Protein Acidic and Rich in Cysteine Injection in Mice Is Towards an Exercise-like Phenotype. [PDF]
Biology (Basel)Ghanemi A, Yoshioka M, St-Amand J.
europepmc +1 more source
Advanced Science, EarlyView.Elevated lactate in diabetes activates the GPR132‐Src pathway in macrophages, inducing macrophage senescence and further enhancing foam cell formation. This mechanism exacerbates atherosclerotic progression. Abstract Diabetes is widely acknowledged as a significant risk factor for atherosclerosis, facilitating plaque formation through various ...
Xiaofeng Ge +10 more
wiley +1 more source
Differential neutrophil responses in murine following intraperitoneal injections of Escherichia coli and Staphylococcus aureus. [PDF]
HeliyonZhu Y, Luo J, Xia X, Feng H, Zhao P.
europepmc +1 more source
An Engineered Soluble Single‐Chain TCR Engager for KRAS‐G12V Specific Tumor Immunotherapy
Advanced Science, EarlyView.This study develops a dimeric T cell receptor engager protein specific for tumor KRAS‐G12V mutation. The engager proteins are capable of mediating the formation of synapse between T cell and tumor cell and demonstrate substantial tumor suppression efficacy.
Keke Ma +14 more
wiley +1 more source
Gut neuropeptide involvement in Parkinson's disease. [PDF]
Am J Physiol Gastrointest Liver PhysiolTempleton HN +2 more
europepmc +1 more source
Advanced Science, EarlyView.Molecular mechanism study of self‐assembled M2pep‐Cs NPs/Plerixafor nanoparticles in targeting MΦ reprogramming by regulating the CXCL12–CXCR4 signaling pathway to enhance immune recognition and clearance of GC (Created by BioRender). Abstract Gastric carcinoma (GC) remains a major global health challenge, requiring novel therapeutic approaches.
Qianqian Cao +9 more
wiley +1 more source