Results 21 to 30 of about 161,020 (308)

Characterization of the T cell receptor repertoire causing collagen arthritis in mice [PDF]

, 1993
Collagen type II-induced arthritis (CIA) is generated in susceptible rodent strains by intradermal injections of homologous or heterologous native type II collagen in complete Freund's adjuvant.
Hood, Leroy E., Kanagawa, Osami, Osman, Gamal-E, Toda, Masaaki   +3 more
core   +2 more sources

Roles of α-Adrenoceptors and Sympathetic Nerve in Acute Herpetic Pain Induced by Herpes Simplex Virus Inoculation in Mice

Journal of Pharmacological Sciences, 2003
Percutaneous inoculation with herpes simplex virus type-1 brings about herpes zoster-like skin lesions, tactile allodynia, and mechanical hyperalgesia in mice.
Atsushi Sasaki, Ichiro Takasaki, Tsugunobu Andoh, Hiroshi Nojima, Kimiyasu Shiraki, Yasushi Kuraishi   +5 more
doaj   +1 more source

Comparison of urine proteome among rat models by intraperitoneal injection with single bacteria and co-injection with two bacteria.

PLoS ONE, 2021
PurposeTo explore and compare urine proteome changes among rat models by intraperitoneal injection with single bacteria and co-injection with two bacteria.MethodEscherichia coli and Staphylococcus aureus are two common human pathogens.
Wenshu Meng, Chenyang Zhao, Youhe Gao
doaj   +2 more sources

Pretreatment with VEGF(R)-inhibitors reduces interstitial fluid pressure, increases intraperitoneal chemotherapy drug penetration, and impedes tumor growth in a mouse colorectal carcinomatosis model [PDF]

, 2015
Cytoreductive surgery combined with intraperitoneal chemotherapy (IPC) is currently the standard treatment for selected patients with peritoneal carcinomatosis of colorectal cancer.
Ceelen, Wim, De Wever, Olivier, Descamps, Benedicte, Gremonprez, Félix, Izmer, Andrei, Vanhaecke, Frank, Vanhove, Christian   +6 more
core   +4 more sources

Enhancement of vaccinia virus based oncolysis with histone deacetylase inhibitors [PDF]

, 2010
Histone deacetylase inhibitors (HDI) dampen cellular innate immune response by decreasing interferon production and have been shown to increase the growth of vesicular stomatitis virus and HSV.
Atkins, H, Bell, JC, Breitbach, C, Cox, J, De Silva, N, Diallo, JS, Falls, T, Guimond, T, Huang, B, Kirn, D, Le Boeuf, F, MacTavish, H, McCart, AJ, Simmons, JG, Stanford, M, Thorne, S   +15 more
core   +1 more source

Morin attenuates L-arginine induced acute pancreatitis in rats by downregulating myeloperoxidase and lipid peroxidation

Asian Pacific Journal of Tropical Biomedicine, 2021
Objective: To explore the therapeutic role of morin against L-arginine-induced acute pancreatitis in rats. Methods: The group 1 received two intraperitoneal injections of normal saline, and groups 2-4 were given two intraperitoneal injections of L ...
Kanwal Rehman, Ummara Rashid, Komal Jabeen, Muhammad Sajid Hamid Akash   +3 more
doaj   +1 more source

A–C Estrogens as Potent and Selective Estrogen Receptor-Beta Agonists (SERBAs) to Enhance Memory Consolidation under Low-Estrogen Conditions [PDF]

, 2018
Estrogen receptor-beta (ERβ) is a drug target for memory consolidation in postmenopausal women. Herein is reported a series of potent and selective ERβ agonists (SERBAs) with in vivo efficacy that are A–C estrogens, lacking the B and D estrogen rings ...
Donaldson, William A., Frick, Karyn M., Hanson, Alicia M., Imhoff, Andrea, Kim, Jaekyoon, Lu, Xingyun, Mackinnon, Alexander Craig, Pandey, Rajesh K., Perera, K. L. Iresha Sampathi, Sem, Daniel S., Sweeney, Noreena, Van Hart, Rochelle M., Wargolet, Adam J.   +12 more
core   +4 more sources

The Protective Effect of Melatonin on Plasma Lipid Profile in Rats with Cerulein-induced Acute Pancreatitis

Türk Spor ve Egzersiz Dergisi, 2019
The objective of this study was to assessment the effect of melatonin on lipid profile in rats with experimentally induced acute pancreatitis. In this study, 32 adult, male, healthy Wistar Abino rats were used. Group I animals was no applied.
Ercan Keskin, Deniz Uluışık
doaj   +1 more source

Efficient Prodrug Activator Gene Therapy by Retroviral Replicating Vectors Prolongs Survival in an Immune-Competent Intracerebral Glioma Model. [PDF]

, 2020
Prodrug activator gene therapy mediated by murine leukemia virus (MLV)-based retroviral replicating vectors (RRV) was previously shown to be highly effective in killing glioma cells both in culture and in vivo.
Chang, Deching, Chang, Hao-Fang, Chen, Bing-Mao, Chen, Shih-Han, Chen, Thomas C, Collins, Sara, Kasahara, Noriyuki, Lin, Sheng-Che, Lu, Yin-Che, Sun, Jui-Ming, Tai, Chien-Kuo, Wang, Hsin-Ell, Wang, Weijun, Wu, Shu-Fen   +13 more
core   +2 more sources

Intratesticular versus intraperitoneal Busulfan administration: a comparative study on spermatogenesis suppression in quails and chickens

Poultry Science
: Generation of transgenic birds can be achieved by temporal suppression of endogenous spermatogenesis in males prior to primordial germ cell implantation.
Noor R. Wattad, Eden Ozer, Stefanie Altgilbers, Claudia Klein, Eyal Cohen, Ohad Zuckrman, Eitan Sessler, Tamar Hadad, Yehonatan Alcalay, Uri Abdu   +9 more
doaj   +1 more source