Results 21 to 30 of about 120,047 (307)

Voluntary wheel running behaviour as a tool to assess the severity in a mouse pancreatic cancer model.

PLoS ONE, 2021
Laboratory animals frequently undergo routine experimental procedures such as handling, restraining and injections. However, as a known source of stress, these procedures potentially impact study outcome and data quality.
Nora Weegh, Eva Zentrich, Dietmar Zechner, Birgitta Struve, Laura Wassermann, Steven Roger Talbot, Simone Kumstel, Miriam Heider, Brigitte Vollmar, André Bleich, Christine Häger   +10 more
doaj   +1 more source

EXPRESSION OF PROTEIN GENES PARTICIPATING IN FIBROPLASTIC PROCESSES IN MICE LUNG DURING THE DEVELOPMENT OF TUBERCULOUS INFLAMMATION

Сибирский научный медицинский журнал, 2019
The study analyzes the expression of protein genes involved in intracellular signaling pathways associated with a profibrotic response, activation of epithelial-mesenchymal and endothelial-mesenchymal transitions, in modeling tuberculous granulomatosis ...
P. M. Kozhin, A. V. Chechushkov, N. S. Zaytseva, M. V. Khrapova, L. A. Cherdantseva, E. B. Menshchikova, A. V. Troitsky, V. A. Shkurupy   +7 more
doaj   +1 more source

Fatal and non-fatal inflammatory injuries induced by different concentrations of L-arginine in Kunming rats

International Journal of Immunopathology and Pharmacology, 2018
To establish animal models of fatal and non-fatal pancreatitis, we randomly divided 55 Kunming rats into three groups: Group A received three intraperitoneal injections of 8% L-arginine (L-arg); Group B received three intraperitoneal injections of 10% L ...
Chunxia Li, Ge Zhang, Aijun Dai, Xiuyan Wang   +3 more
doaj   +1 more source

Design and Implementation of the Dual-Hormone Artificial Pancreas in Animal Studies – A Model Predictive Control Approach with Intraperitoneal Hormone Injections [PDF]

, 2023
In this thesis, the exploration of new ways to help people with Type 1 Diabetes better control their condition is described. In this research, our primary focus was on the feasibility and benefits of utilizing the intraperitoneal (IP) route for insulin ...
Davari Benam, Karim
core   +1 more source

Effects of bioflavonoid ternatin on liver regeneration and oxidative stress in rats [PDF]

Acta Cirúrgica Brasileira, 2013
PURPOSE: To evaluate the effect of bioflavonoid ternatin (TRT) on rat liver regeneration and oxidative stress after 70% partial hepatectomy (PH). METHODS: Thirty six young male Wistar rats were randomly assigned to two groups of 18 animals each - control
José Ulisses de Souza Melo, Radamés Bezerra Melo, Jefferson Menezes Viana Santos, Manoel Messias Campos Júnior, Sérgio Botelho Guimarães, Paulo Roberto Leitão Vasconcelos   +5 more
doaj   +4 more sources

Intraperitoneal Glucose Transport to Micrometastasis: A Multimodal In Vivo Imaging Investigation in a Mouse Lymphoma Model

, 2021
Bc-DLFL.1 is a novel spontaneous, high-grade transplantable mouse B-cell lymphoma model for selective serosal propagation. These cells attach to the omentum and mesentery and show dissemination in mesenteric lymph nodes. We aimed to investigate its early
Nikolett Hegedűs, Erzsébet Schmidt, Katalin Zámbó, Dániel Dezső, Hussain Alizadeh, David Tuch, Zsombor Ritter, Dávid Szöllősi, Xinkai Jia, Péter Balogh, Ildikó Horváth, Domokos Máthé, Kunal Vyas   +12 more
core   +1 more source

Roles of α-Adrenoceptors and Sympathetic Nerve in Acute Herpetic Pain Induced by Herpes Simplex Virus Inoculation in Mice

Journal of Pharmacological Sciences, 2003
Percutaneous inoculation with herpes simplex virus type-1 brings about herpes zoster-like skin lesions, tactile allodynia, and mechanical hyperalgesia in mice.
Atsushi Sasaki, Ichiro Takasaki, Tsugunobu Andoh, Hiroshi Nojima, Kimiyasu Shiraki, Yasushi Kuraishi   +5 more
doaj   +1 more source

Effects of ionizing radiation in combination with Erufosine on T98G glioblastoma xenograft tumours: a study in NMRI nu/nu mice

Radiation Oncology, 2012
Background Erufosine is a promising anticancer drug that increases the efficacy of radiotherapy in glioblastoma cell lines in vitro. Moreover, treatment of nude mice with repeated intraperitoneal or subcutaneous injections of Erufosine is well tolerated ...
Henke Guido, Meier Verena, Lindner Lars H, Eibl Hansjörg, Bamberg Michael, Belka Claus, Budach Wilfried, Jendrossek Verena   +7 more
doaj   +1 more source

Comparison of urine proteome among rat models by intraperitoneal injection with single bacteria and co-injection with two bacteria.

PLoS ONE, 2021
PurposeTo explore and compare urine proteome changes among rat models by intraperitoneal injection with single bacteria and co-injection with two bacteria.MethodEscherichia coli and Staphylococcus aureus are two common human pathogens.
Wenshu Meng, Chenyang Zhao, Youhe Gao
doaj   +2 more sources

Morin attenuates L-arginine induced acute pancreatitis in rats by downregulating myeloperoxidase and lipid peroxidation

Asian Pacific Journal of Tropical Biomedicine, 2021
Objective: To explore the therapeutic role of morin against L-arginine-induced acute pancreatitis in rats. Methods: The group 1 received two intraperitoneal injections of normal saline, and groups 2-4 were given two intraperitoneal injections of L ...
Kanwal Rehman, Ummara Rashid, Komal Jabeen, Muhammad Sajid Hamid Akash   +3 more
doaj   +1 more source