Results 31 to 40 of about 300,512 (305)

Comparison of urine proteome among rat models by intraperitoneal injection with single bacteria and co-injection with two bacteria.

open access: yesPLoS ONE, 2021
PurposeTo explore and compare urine proteome changes among rat models by intraperitoneal injection with single bacteria and co-injection with two bacteria.MethodEscherichia coli and Staphylococcus aureus are two common human pathogens.
Wenshu Meng, Chenyang Zhao, Youhe Gao
doaj   +2 more sources

Blood lactate dynamics in awake and anaesthetized mice after intraperitoneal and subcutaneous injections of lactate—sex matters [PDF]

open access: yes, 2020
Lactate treatment has shown a therapeutic potential for several neurological diseases, including Alzheimer’s disease. In order to optimize the administration of lactate for studies in mouse models, we compared blood lactate dynamics after intraperitoneal
Haugen, Øyvind Pernell   +6 more
core   +1 more source

The Protective Effect of Melatonin on Plasma Lipid Profile in Rats with Cerulein-induced Acute Pancreatitis

open access: yesTürk Spor ve Egzersiz Dergisi, 2019
The objective of this study was to assessment the effect of melatonin on lipid profile in rats with experimentally induced acute pancreatitis. In this study, 32 adult, male, healthy Wistar Abino rats were used. Group I animals was no applied.
Ercan Keskin, Deniz Uluışık
doaj   +1 more source

Histhopathological Investigation of the Intraperitoneal Injection of Starch-Graft-Polyaniline/Magnesium Oxide (Chitosan/MgO) Nanocomposites on Liver and Kidney of Rats

open access: yesمجله دانشکده پزشکی اصفهان, 2019
Background: At the present study, we assessed the effects of intraperitoneal injections of nanocomposite of Starch-Graft-Polyaniline/Magnesium Oxide (Chitosan/MgO) on liver and kidney of male rats. Methods: 28 male rats were randomly allocated into four
Mohammadreza Hajinezhad   +1 more
doaj   +1 more source

Morin attenuates L-arginine induced acute pancreatitis in rats by downregulating myeloperoxidase and lipid peroxidation

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2021
Objective: To explore the therapeutic role of morin against L-arginine-induced acute pancreatitis in rats. Methods: The group 1 received two intraperitoneal injections of normal saline, and groups 2-4 were given two intraperitoneal injections of L ...
Kanwal Rehman   +3 more
doaj   +1 more source

DELAY OR INHIBITION OF CONVULSIONS BY INTRAPERITONEAL INJECTIONS OF DIVERSE SUBSTANCES

open access: yes, 1967
Prior intraperitoneal injections, into mice or rats, of strong solutions of γ-aminobutyric acid, DL-alanine, other amino acids, succinate, or sucrose tend to postpone or prevent convulsions and death caused by the administration of oxygen at high ...
K. A. C. Elliott, F. V. DeFeudis
core   +1 more source

Repeated intraperitoneal injections of saline attenuate the antibody response to a subsequent intraperitoneal injection of antigen

open access: yesBrain, Behavior, and Immunity, 1989
The results of two experiments with male C3H/HeJ mice indicated that repeated intraperitoneal (ip) injections of sterile saline over a 2-week period resulted in an attenuated antibody response to the subsequent ip injection of a soluble protein antigen, keyhole limpet hemocyanin.
J, Moynihan   +4 more
openaire   +2 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Can Human Recombinant Epidermal Growth Factor Improve Ischemia and Induce Healing of Anastomosis in an Experimental Study in a Rabbit Model?

open access: yesJournal of Investigative Surgery, 2017
Purpose: Anastomotic leaks following intestinal operations may cause devastating effects on patients. Ischemia may also occur at the intestinal walls in the presence of strangulations.
Rahman Şenocak   +6 more
doaj   +1 more source

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