Results 31 to 40 of about 163,246 (289)

A–C Estrogens as Potent and Selective Estrogen Receptor-Beta Agonists (SERBAs) to Enhance Memory Consolidation under Low-Estrogen Conditions [PDF]

open access: yes, 2018
Estrogen receptor-beta (ERβ) is a drug target for memory consolidation in postmenopausal women. Herein is reported a series of potent and selective ERβ agonists (SERBAs) with in vivo efficacy that are A–C estrogens, lacking the B and D estrogen rings ...
Donaldson, William A.   +12 more
core   +4 more sources

Intratesticular versus intraperitoneal Busulfan administration: a comparative study on spermatogenesis suppression in quails and chickens

open access: yesPoultry Science
: Generation of transgenic birds can be achieved by temporal suppression of endogenous spermatogenesis in males prior to primordial germ cell implantation.
Noor R. Wattad   +9 more
doaj   +1 more source

The Protective Effect of Melatonin on Plasma Lipid Profile in Rats with Cerulein-induced Acute Pancreatitis

open access: yesTürk Spor ve Egzersiz Dergisi, 2019
The objective of this study was to assessment the effect of melatonin on lipid profile in rats with experimentally induced acute pancreatitis. In this study, 32 adult, male, healthy Wistar Abino rats were used. Group I animals was no applied.
Ercan Keskin, Deniz Uluışık
doaj   +1 more source

Morin attenuates L-arginine induced acute pancreatitis in rats by downregulating myeloperoxidase and lipid peroxidation

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2021
Objective: To explore the therapeutic role of morin against L-arginine-induced acute pancreatitis in rats. Methods: The group 1 received two intraperitoneal injections of normal saline, and groups 2-4 were given two intraperitoneal injections of L ...
Kanwal Rehman   +3 more
doaj   +1 more source

Pretreatment with VEGF(R)-inhibitors reduces interstitial fluid pressure, increases intraperitoneal chemotherapy drug penetration, and impedes tumor growth in a mouse colorectal carcinomatosis model [PDF]

open access: yes, 2015
Cytoreductive surgery combined with intraperitoneal chemotherapy (IPC) is currently the standard treatment for selected patients with peritoneal carcinomatosis of colorectal cancer.
Ceelen, Wim   +6 more
core   +4 more sources

Histhopathological Investigation of the Intraperitoneal Injection of Starch-Graft-Polyaniline/Magnesium Oxide (Chitosan/MgO) Nanocomposites on Liver and Kidney of Rats

open access: yesمجله دانشکده پزشکی اصفهان, 2019
Background: At the present study, we assessed the effects of intraperitoneal injections of nanocomposite of Starch-Graft-Polyaniline/Magnesium Oxide (Chitosan/MgO) on liver and kidney of male rats. Methods: 28 male rats were randomly allocated into four
Mohammadreza Hajinezhad   +1 more
doaj   +1 more source

Corticosterone Acts in the Nucleus Accumbens to Enhance Dopamine Signaling and Potentiate Reinstatement of Cocaine Seeking [PDF]

open access: yes, 2013
Stressful life events are important contributors to relapse in recovering cocaine addicts, but the mechanisms by which they influence motivational systems are poorly understood.
Baker, David A.   +10 more
core   +2 more sources

Resveratrol given intraperitoneally does not inhibit the growth of high-risk t(4;11) acute lymphoblastic leukemia cells in a NOD/SCID mouse model. [PDF]

open access: yes, 2011
The efficacy of resveratrol as a preventive agent against the growth of t(4;11) acute lymphoblastic leukemia (ALL) was evaluated in NOD.CB17-Prkdcscid/J mice engrafted with the human t(4;11) ALL SEM cell line.
Ducore, Jonathan M   +5 more
core   +1 more source

Suppression of antibody formation by the reticuloendothelial (RES)-blockade. I. Effects of the RES-blockade with macromolecular polyvinyl pyrrolidone [PDF]

open access: yes, 1968
For the purpose of revealing the role of the reticuloendothelial system (RES) for the antibody formation, the rats which received the repeated intraperitoneal and subcutaneous injections of a vast amount of PVP were challenged by bovine serum albumin ...
Ohbuchi, Shinji
core   +1 more source

Superparamagnetic iron oxide polyacrylic acid coated {\gamma}-Fe2O3 nanoparticles does not affect kidney function but causes acute effect on the cardiovascular function in healthy mice

open access: yes, 2012
This study describes the distribution of intravenously injected polyacrylic acid (PAA) coated {\gamma}-Fe2O3 NPs (10 mg kg-1) at the organ, cellular and subcellular levels in healthy BALB/cJ mice and in parallel addresses the effects of NP injection on ...
Baatrup, Erik   +10 more
core   +2 more sources

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