Practice Patterns of Physicians Who Perform Lumbar Interlaminar Epidural Steroid Injections: A Technical Survey. [PDF]
Hasoon J +8 more
europepmc +1 more source
Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing +10 more
wiley +1 more source
Chronic Pain in Elderly Patients: Pathophysiology, Pharmacologic and Non-Pharmacologic Therapies, and Interventional Management. [PDF]
Jain A +6 more
europepmc +1 more source
Engineering Neuronal Network Connectivity Through Precise and Scalable Electrical Modulation
This study presents a scalable all‐electrical method for precise neuronal‐circuit reconfiguration based on high‐density microelectrode arrays. By employing biologically inspired plasticity rules, targeted connectivity changes were successfully induced and quantified across diverse neuronal preparations.
Sreedhar S. Kumar +10 more
wiley +1 more source
Improved Pain and Function Using Multiphase Spinal Cord Stimulation in a Nonsurgical Spine Patient. [PDF]
Hasoon J, Urits I, Viswanath O.
europepmc +1 more source
Ovarian macrophage depletion reverses OHSS resistance in estrildid finches and exacerbates OHSS symptoms in rats. Activating macrophage GPR183 alleviates OHSS by reducing pro‐inflammatory factors, increasing immunomodulatory molecules, remodeling CD44/SDC4‐mediated communication, and restoring immune homeostasis.
Xiaofei Yan +11 more
wiley +1 more source
Correction to: No drugs, more sex? And Rock'n Roll: effective non-operative treatments and practical management strategies for older adults with lumbar spinal stenosis. [PDF]
Ammendolia C.
europepmc +1 more source
This study reveals the dual role of celecoxib in intervertebral disc degeneration. While low concentrations are protective, high concentrations induce toxicity by upregulating HSP90, which synergizes with USP15 to deubiquitinate and stabilize RBX1. This leads to degradation of COMMD1/ATP7B, copper dyshomeostasis, and ultimately, cuproptosis.
Youfeng Guo +11 more
wiley +1 more source
Effectiveness of epidural steroid injections for low back pain in older adults: a systematic review. [PDF]
Zhu AC +6 more
europepmc +1 more source

