Results 51 to 60 of about 1,490 (268)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Research and exploration on Shaanxi Coal Group’s 4 million t/a CO2 capture and storage technology

open access: yesMeitan xuebao
While modern coal chemical industry addresses national energy security demands, its exploration of green development pathways featuring source emission reduction and terminal decarbonization holds significant implications for global climate change ...
Jiang XIAO   +7 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

MATHEMATICAL STATISTICS AS A TOOL FOR ANALYZING THE EFFECTIVENESS OF MEASURES IN OIL PRODUCTION

open access: yesИзвестия высших учебных заведений: Нефть и газ, 2015
The article discusses the results of unifactor associative, multiple-factor variance and statistical correlation analyses of various geological and technological parameters influence on the injection wells water-intake rate in one of producing formations
E. F. Zakharova, E. V. Levanova
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Injective and non-injective realizations with symmetry

open access: yesContributions to Discrete Mathematics, 2010
In this paper, we introduce a natural classification of bar and joint frameworks that possess symmetry. This classification establishes the mathematical foundation for extending a variety of results in rigidity, as well as infinitesimal or static rigidity, to frameworks that are realized with certain symmetries and whose joints may or may not be ...
openaire   +2 more sources

SUBCONJUNCTIVAL INJECTIONS. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1896
n ...
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Filtered Products of Copies of Injective Modules

open access: yesAxioms
We study the transfer of injectivity to filtered products of copies of an injective module. This leads to the introduction of a generalized Noetherian condition, the so-called (ℵ,M)-Noetherian rings. We prove that M is F-injective for every filter F with
Driss Bennis   +3 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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