Results 101 to 110 of about 5,170,040 (364)
FEBS Open Bio, EarlyView.In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley +1 more source
BMC Cardiovascular DisordersBackground Acute coronary syndrome (ACS) is frequently reported in patients with coronavirus disease 2019 (COVID-19). Cytokine storm induced by interleukin-6 (IL-6) has been suggested to potentially cause myocardial injury in COVID-19.
Mohsen Sedighi +6 more
doaj +1 more source
Racial disparities in pedestrian-related injury hospitalizations in the United States
BMC Public Health, 2020 Background Racial/ethnic disparity has been documented in a wide variety of health outcomes, and environmental components are contributors. For example, food deserts have been tied to obesity rates.
Cara Hamann +2 more
doaj +1 more source
Built to Last: Functional and structural mechanisms in the moth olfactory network mitigate effects of neural injury [PDF]
arXiv, 2018 Most organisms suffer neuronal damage throughout their lives, which can impair performance of core behaviors. Their neural circuits need to maintain function despite injury, which in particular requires preserving key system outputs. In this work, we explore whether and how certain structural and functional neuronal network motifs act as injury ...
arxiv
Injury epidemiology and publishing injury research
Journal of Injury and Violence Research, 2012 In the Dictionary of Epidemiology, Professor Last offers the following definition: “Epidemiology is the study of the distribution and determinants of health-related states or events in specified populations, and the application of this study to the control of health problems”.1 I similarly try to define injury epidemiology as the study of the ...
openaire +4 more sources
FEBS Open Bio, EarlyView.The K+‐Cl− cotransporters (KCCs) facilitate the symport of ions across the plasma membrane. They participate in physiological processes including neuronal regulation. Here, we characterized KCCs from Drosophila and Hydra vulgaris. Comparative analyses of transporters provide insights into the mechanism of KCC ion transport, regulation, and evolution ...
Satoshi Fudo +4 more
wiley +1 more source
Iowa Plan for Brain Injury, October 2002 – September 2005 [PDF]
, 2002 Cutting edge emergency services now allow many Iowans to survive a traumatic brain injury (TBI) that would have caused death just a decade ago.
core
Continuous infusion of an agonist of the tumor necrosis factor receptor 2 in the spinal cord improves recovery after traumatic contusive injury. [PDF]
, 2019 AimThe activation of the TNFR2 receptor is beneficial in several pathologies of the central nervous system, and this study examines whether it can ameliorate the recovery process following spinal cord injury.MethodsEHD2-sc-mTNFR2 , an agonist specific ...
Bethea, John R +10 more
core +2 more sources
Automated rapidplan model validation using Eclipse scripting API
Journal of Applied Clinical Medical Physics, EarlyView.Abstract RapidPlan offers efficiency gains and quality improvements in treatment planning. Prior to its use in the clinic, it requires an extensive validation procedure in which established clinical plans and those generated by the model are compared. The manual iterative nature of this process is resource intensive, as numerous iterations are required
Bradley Beeksma +2 more
wiley +1 more source
A Laser-Guided Spinal Cord Displacement Injury in Adult Mice [PDF]
, 2018 Mouse models are unique for studying molecular mechanisms of neurotrauma because of the availability of various genetic modified mouse lines. For spinal cord injury (SCI) research, producing an accurate injury is essential, but it is challenging because ...
Bakare, Adewale A. +7 more
core +1 more source