Results 61 to 70 of about 3,029,061 (317)
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Journal of Taibah University Medical Sciences, 2020 الملخص: أهداف البحث: على الرغم من الانتشار المتزايد للغرق، فإن سلوكيات البحث عن الرعاية الطبية بين ضحايا الغرق لا تزال غير مستكشفة في بنغلاديش. تهدف هذه الدراسة إلى استكشاف سلوكيات البحث عن الرعاية الطبية بين ضحايا الغرق في بنغلاديش.
Mohammad J. Hossain, MPH +5 more
doaj +1 more source
Editorial – Bicycle injuries and injury prevention [PDF]
Chronic Diseases and Injuries in Canada, 2014 In 1989, long before this journal added injuries to its title, it published two papers on childhood injuries and I was asked to write an editorial for this occasion. I chose the title "Challenges for Injury Prevention: Two Neglected Aspects" because I thought the papers neglected to mention the inadequacy of injury statistics (at the time there were no
openaire +2 more sources
Outcomes following childhood head injury : a population study [PDF]
, 2004 Objectives: To identify outcomes following head injury (HI) amongst a population of children admitted to one hospital centre and compare outcomes between different severity groups. Methods:A postal follow-up of children admitted with HI to one NHS Trust,
Magnay, Andrew R. +3 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Establishing an injury indicator for severe paediatric injury [PDF]
Injury Prevention, 2015 BackgroundRoutinely gathered injury data, such as hospitalisations, may be subject to variation from sources other than injury incidence. There is a need for an indicator that defines severe injury, which may be less vulnerable to fluctuations due to changes in care policies.
Ian, Pike +5 more
openaire +3 more sources
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Journal of Orthopaedic Surgery and ResearchPurpose To evaluate the effects of mixed reality (MR)–assisted navigation compared with conventional manual positioning on operative time and tunnel positioning accuracy during anterior cruciate ligament reconstruction (ACLR) using 3D-printed knee models.
Binyang Meng +9 more
doaj +1 more source
, 2001 Injury mortality is the fourth commonest cause of death in Ireland. The treatment of injuries has a major impact on our hospitals and on our budget for health. Long term disability following accidents is a serious problem.
Laffoy, M. +4 more
core
Folic Acid Enhances Early Functional Recovery in a Piglet Model of Pediatric Head Injury [PDF]
, 2010 For stroke and spinal cord injury, folic acid supplementation has been shown to enhance neurodevelopment and to provide neuroprotection. We hypothesized that folic acid would reduce brain injury and improve neurological outcome in a neonatal piglet model
Jill Ralston +13 more
core +1 more source