Results 81 to 90 of about 5,170,040 (364)
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
New Universal Theory of Injury Prediction and Prevention [PDF]
arXiv, 2009 The prediction and prevention of traumatic brain injury, spinal injury and general musculo-skeletal injury is a very important aspect of preventive medical science. Recently, in a series of papers, I have proposed a new coupled loading-rate hypothesis as a unique cause of all above injuries.
arxiv
Hyperacute pathophysiology of traumatic and vascular brain injury captured by ultrasound, photoacoustic, and magnetic resonance imaging [PDF]
arXiv, 2022 Cerebrovascular dynamics and pathomechanisms that evolve in the minutes and hours following traumatic vascular injury in the brain remain largely unknown. We investigated the pathophysiology evolution within the first three hours after closed-head traumatic brain injury (TBI) and subarachnoid hemorrhage (SAH), two common traumatic vascular injuries, in
arxiv
FEBS Open Bio, EarlyView.Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui +15 more
wiley +1 more source
Burns & Trauma, 2017 Background Burn is one of the major public health problems in Bangladesh. Specialized personnel and technologies are required, however, in many cases they are not readily available. Taking the situation into account, Interplast Australia and New Zealand,
Animesh Biswas +5 more
doaj +1 more source
Hippocampal interneuronal dysfunction and hyperexcitability in a porcine model of concussion
Communications Biology, 2023 Cognitive impairment is a common symptom following mild traumatic brain injury (mTBI or concussion) and can persist for years in some individuals.
Alexandra V. Ulyanova +10 more
doaj +1 more source
NFL Injuries Before and After the 2011 Collective Bargaining Agreement (CBA) [PDF]
arXiv, 2018 The National Football League's (NFL) 2011 collective bargaining agreement (CBA) with its players placed a number of contact and quantity limitations on practices and workouts. Some coaches and others have expressed a concern that this has led to poor conditioning and a subsequent increase in injuries. We sought to assess whether the 2011 CBA's practice
arxiv
Biomechanical Tolerance of Whole Lumbar Spines in Straightened Posture Subjected to Axial Acceleration [PDF]
, 2017 Quantification of biomechanical tolerance is necessary for injury prediction and protection of vehicular occupants. This study experimentally quantified lumbar spine axial tolerance during accelerative environments simulating a variety of military and ...
Baisden, Jamie L. +9 more
core +2 more sources