Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao +8 more
wiley +1 more source
On-scene predictors of injury severity, deterioration, and death following road injury: a systematic scoping review of information available to responders and its use in triage tools. [PDF]
Gluyas-Harris J +3 more
europepmc +1 more source
Shape‐Morphing Nanoengineered Hydrogel Ribbons as Hemostats
This study introduces a self‐assembling, shape‐morphing nanoengineered hydrogel ribbon system that rapidly forms porous aggregates in situ for efficient hemostasis in trauma and surgical applications. Abstract Rapid and effective hemorrhage control remains a major challenge in trauma and surgical care, particularly for complex or noncompressible wounds.
Ryan Davis Jr +9 more
wiley +1 more source
Patterns of sex-specific outcomes and mortality in polytrauma: a demographic and epidemiologic analysis by injury severity score. [PDF]
Brauckmann V +5 more
europepmc +1 more source
Adaptive 4D‐Printed Vascular Stents With Low‐Temperature‐Activated and Intelligent Deployment
Microarchitected coronary artery stents were fabricated using a polycaprolactone (PCL)‐based shape memory polymer (SMP) composite via projection micro‐stereolithography (PµSL) 4D printing. By incorporating diethyl phthalate (DEP) as a plasticizer, the thermal transition temperature (Ttran) was modulated to about 37°C, enabling rapid and autonomous ...
Yannan Li +12 more
wiley +1 more source
A validated CT-based scoring system for lateral compression type one pelvic ring injuries provides insight into the spectrum of injury severity and guides treatment decisions; a prospective study. [PDF]
Therrien CC +6 more
europepmc +1 more source
Real‐Time, Label‐Free Monitoring of Cell Behavior on a Bioelectronic Scaffold
A bioelectronic nanofibrous scaffold is introduced that supports cell growth while enabling real‐time, label‐free monitoring of cellular behavior through impedance measurements. The system correlates electrical signals with cell viability and surface coverage, offering an integrated platform for studying dynamic biological processes and advancing next ...
Dana Cohen‐Gerassi +10 more
wiley +1 more source
Prognostic value of the lactate-albumin ratio in trauma: A comparison with shock index and injury severity score. [PDF]
Park J +12 more
europepmc +1 more source
An Ionic Gelation Powder for Ultrafast Hemostasis and Accelerated Wound Healing
An ultrafast ionic gelation‐activated hemostatic powder (AGCL) forms a hydrogel within ≈1 s upon contact with blood‐derived calcium ions. The AGCL powder enables rapid hemorrhage control, strong tissue adhesion, and enhanced healing. The powder's pre‐crosslinked polymer network ensures high blood uptake and stability, offering effective treatment for ...
Youngju Son +12 more
wiley +1 more source

