Results 11 to 20 of about 849 (182)

Modified rush venom immunotherapy in dogs with Hymenoptera hypersensitivity

Veterinary Dermatology, Volume 34, Issue 6, Page 532-542, December 2023., 2023
Background – Hymenoptera envenomation occurs frequently in people and dogs and can trigger anaphylaxis. Venom immunotherapy (VIT) is the only preventative treatment for Hymenoptera hypersensitivity and is indicated for people with severe adverse reactions to insect stings. Rush VIT is an accelerated VIT induction schedule performed in people.
Alexandra Moore, Amanda K. Burrows, Wayne S. Rosenkrantz, Rudayna M. Ghubash, Giselle Hosgood   +4 more
wiley   +1 more source

The safety of rush immunotherapy in the management of canine atopic dermatitis—230 cases

Veterinary Dermatology, Volume 34, Issue 5, Page 385-392, October 2023., 2023
Background – The duration of the induction phase of allergen‐specific immunotherapy conventionally is a period of several weeks, during which the volume of an allergen solution, administered by injection, is gradually increased until the maintenance dose is reached.
Tamara Weitzer, Ralf Mueller
wiley   +1 more source

Equine allergic skin diseases: Clinical consensus guidelines of the World Association for Veterinary Dermatology

Veterinary Dermatology, Volume 34, Issue 3, Page 175-208, June 2023., 2023
Abstract Background Allergic skin diseases are common in horses worldwide. The most common causes are insect bites and environmental allergens. Objectives To review the current literature and provide consensus on pathogenesis, diagnosis, treatment and prevention. Materials and Methods The authors reviewed the literature up to November 2022.
R. Marsella, S. White, V. A. Fadok, D. Wilson, R. Mueller, C. Outerbridge, W. Rosenkrantz   +6 more
wiley   +1 more source

Impact of Pre-Treatment Serum Ferritin on Response and Survival in Myelodysplastic Syndromes Treated With Azacytidine: A Multivariate Analysis. [PDF]

Cancer Med
Elevated serum ferritin levels before treatment with azacytidine are associated with lower response rates and shorter survival in patients with myelodysplastic syndromes. This study supports the early identification of transfusion‐related iron overload to improve treatment planning.
Carrasco GM, Flores RMO, Delgado RG, Morcillo BC, Rosell Mas AI, Díaz Canales D, González MR, Gomariz MC, Escamilla-Sánchez A.   +8 more
europepmc   +2 more sources

A randomised, double‐blinded comparison between subcutaneous rush and intralympathic allergen immunotherapy induction in atopic dogs

Veterinary Dermatology, Volume 34, Issue 2, Page 91-98, April 2023., 2023
Background – Atopic dermatitis (AD) is one of the most common skin diseases in small animal practice. Allergen immunotherapy (AIT) is the only curative treatment for the disease, and oral, subcutaneous and intralymphatic administration of allergens are commonly employed.
Ralf S. Mueller, Yuri Zablotski, Katja Baumann, Teresa Boehm, Bettina Kasper, Christoph Klinger, Maarten Monke, Laura Udraite‐Vovk, Tamara Weitzer, Natalie K. Y. Gedon   +9 more
wiley   +1 more source

Efficacy of subcutaneous allergen immunotherapy in atopic dogs: A retrospective study of 664 cases

Veterinary Dermatology, Volume 33, Issue 4, Page 321-e75, August 2022., 2022
Background –Canine atopic dermatitis (cAD) is an allergic skin disease affecting approximately 10% of dogs. Allergen immunotherapy (AIT) is currently the only treatment option able to induce tolerance to the causative allergens. Objective – To retrospectively establish the efficacy of AIT in atopic dogs.
Evelien E. M. Fennis, Catharina M. M. van Damme, Yvette M. Schlotter, Jacqueline D. Sinke, Mieke H. G. Leistra, Richard T. Bartels, Femke Broere   +6 more
wiley   +1 more source

Is there a role for HSF1 in viral infections?

FEBS Open Bio, Volume 12, Issue 6, Page 1112-1124, June 2022., 2022
Heat shock factor 1 (HSF1) plays important roles in the replication cycle of viruses. Numerous viruses have been found to modulate, or to be affected by the activation of HSF1. Depending on the virus, HSF1 can lead to detrimental effects over the virus (red line) or confer advantages to the virus (green arrows). Understanding the interplay between HSF1
Antonia Reyes, Areli J. Navarro, Benjamín Diethelm‐Varela, Alexis M. Kalergis, Pablo A. González   +4 more
wiley   +1 more source

Immunotherapy using pullulan-conjugated Der f 2 allergen in canine atopic dermatitis: An anti-inflammatory agent-sparing approach. [PDF]

Vet Dermatol
Background – Allergen immunotherapy is used as aetiological treatment for canine atopic dermatitis (cAD). Objective – To assess the anti‐inflammatory agent‐sparing effect over 1 year of immunotherapy using pullulan‐conjugated recombinant Der f 2 (rDf2‐P). Conclusions and Clinical Relevance – Der f 2‐P immunotherapy can lead to a rapid reduction in anti‐
Nagata M, Kozakai J, Yoshida A, Kameyama K, Oboso H, Muto H, Ogino S, Tsukui T.   +7 more
europepmc   +2 more sources

Host–virus relationships: a sum of many battles

FEBS Open Bio, Volume 12, Issue 6, Page 1094-1095, June 2022., 2022
The spread of pathogenic viruses implies host infection, replication, and virus dissemination. In each step, viruses have to overcome the host defenses designed to neutralize the threat they pose. The host–virus relationship represents a constant multistage battle for power as the host/cell does not voluntarily give in to the viral enemy.
Marcelo López‐Lastra
wiley   +1 more source

Immunopathogenesis and immunotherapy of Culicoides hypersensitivity in horses: an update

Veterinary Dermatology, Volume 32, Issue 6, Page 579-e156, December 2021., 2021
Culicoides hypersensitivity (CH) is a strongly pruritic dermatitis of horses, characterised histologically by mixed perivascular to diffuse cellular infiltrates of mononuclear cells and eosinophils, and caused by helper T cell (Th)2, immunoglobulin (Ig)E‐mediated reactions to antigens present in the saliva of biting Culicoides midges.
Eliane Marti, Ella N. Novotny, Iva Cvitas, Anja Ziegler, A. Douglas Wilson, Sigurbjörg Torsteinsdottir, Antonia Fettelschoss‐Gabriel, Sigridur Jonsdottir   +7 more
wiley   +1 more source