Immunopathogenesis and immunotherapy of Culicoides hypersensitivity in horses: an update
Culicoides hypersensitivity (CH) is a strongly pruritic dermatitis of horses, characterised histologically by mixed perivascular to diffuse cellular infiltrates of mononuclear cells and eosinophils, and caused by helper T cell (Th)2, immunoglobulin (Ig)E‐mediated reactions to antigens present in the saliva of biting Culicoides midges.
Eliane Marti +7 more
wiley +1 more source
Reproducibility of serum testing for environmental allergen‐specific IgE in dogs in Europe
Background – Serum testing for allergen‐specific immunoglobulin (Ig)E is commonly employed to identify allergens used for allergen‐specific immunotherapy in dogs, yet the reliability of results has been a matter of debate. Objective – The aim of this study was to evaluate the reproducibility of serum tests for environmental allergen‐specific IgE in ...
Katja N. Baumann +4 more
wiley +1 more source
The Critical Role of Oxidative Stress in Sarcopenic Obesity
Sarcopenic obesity (SO) is a combination of obesity and sarcopenia that primarily develops in older people. Patients with SO have high fat mass, low muscle mass, low muscle strength, and low physical function. SO relates to metabolic syndrome and an increased risk of morbimortality.
Andrea Gonzalez +6 more
wiley +1 more source
Redox‐Dependent Effects in the Physiopathological Role of Bile Acids
Bile acids (BA) are recognized by their role in nutrient absorption. However, there is growing evidence that BA also have endocrine and metabolic functions. Besides, the steroidal‐derived structure gives BA a toxic potential over the biological membrane. Thus, cholestatic disorders, characterized by elevated BA on the liver and serum, are a significant
Josué Orozco-Aguilar +3 more
wiley +1 more source
Contribution of Gut Microbiota to Immune Tolerance in Infants
The prevalence of food allergy has increased in recent years, especially among the pediatric population. Differences in the gut microbiota composition between children with FA and healthy children have brought this topic into the spotlight as a possible explanation for the increase in FA.
Constanza S. Méndez +3 more
wiley +1 more source
Manifestaciones cardiovasculares asociadas a la inmunoterapia [PDF]
La inmunoterapia comprende la utilización de los inhibidores de puntos de control en los que durante el tratamiento se ha documentado un amplio espectro de eventos adversos relacionados con el sistema inmunitario que afectan al corazón.
Figueredo-Guerra, Elianis de la Caridad +3 more
core +1 more source
Immunotherapy using pullulan-conjugated Der f 2 allergen in canine atopic dermatitis: An anti-inflammatory agent-sparing approach. [PDF]
Background – Allergen immunotherapy is used as aetiological treatment for canine atopic dermatitis (cAD). Objective – To assess the anti‐inflammatory agent‐sparing effect over 1 year of immunotherapy using pullulan‐conjugated recombinant Der f 2 (rDf2‐P). Conclusions and Clinical Relevance – Der f 2‐P immunotherapy can lead to a rapid reduction in anti‐
Nagata M +7 more
europepmc +2 more sources
Impact of Pre-Treatment Serum Ferritin on Response and Survival in Myelodysplastic Syndromes Treated With Azacytidine: A Multivariate Analysis. [PDF]
Elevated serum ferritin levels before treatment with azacytidine are associated with lower response rates and shorter survival in patients with myelodysplastic syndromes. This study supports the early identification of transfusion‐related iron overload to improve treatment planning.
Carrasco GM +8 more
europepmc +2 more sources
Inmunoterapia en el asma bronquial [PDF]
La inmunoterapia surgio en 1911 con vocacion para el tratamiento de las afecciones secundarias al estado atopico. Hoy dia permanece abierta la polemica, en algunos casos visceral, sobre la efectividad de dicha modalidad terapeutica, principalmente en el ...
Hernández Utrera, Fernando
core +1 more source
Nonalcoholic fatty liver disease (NAFLD) is a pathology that contains a broad liver dysfunctions spectrum. These alterations span from noninflammatory isolated steatosis until nonalcoholic steatohepatitis (NASH), a more aggressive form of the disease characterized by steatosis, inflammatory status, and varying liver degrees fibrosis.
Andrea Gonzalez +7 more
wiley +1 more source

