Regulatory Networks Driving the Specification, Differentiation, and Diversification of Neurons in the Mouse Inner Ear. [PDF]
J Assoc Res OtolaryngolPavlinkova G +4 more
europepmc +1 more source
CHARGE Syndrome: What an Otolaryngologist Should Know—A Systematic Review and Meta‐Analysis
Otolaryngology–Head and Neck Surgery, EarlyView.Abstract Objective To synthesize the prevalence of otolaryngologic manifestations in CHARGE syndrome (CS) to support otolaryngologists in delivering comprehensive management. Data Sources PubMed/MEDLINE, Embase, and Google Scholar were searched for English‐ and French‐language studies published from January 1980 through January 2025.
Camille Caron +5 more
wiley +1 more source
Effects of pregnancy and pregnancy-related conditions on the inner ear: a systematic review. [PDF]
J Laryngol OtolTimms S, Stapleton E.
europepmc +1 more source
Restoration, Not Bypass: Otoferlin Gene Therapy and a New Era in Hearing Loss Treatment
Otolaryngology–Head and Neck Surgery, EarlyView.Abstract The FDA approval of Otarmeni, an AAV‐based gene therapy for biallelic OTOF‐associated sensorineural hearing loss, represents a conceptual shift in otology: from bypassing defective auditory physiology to restoring it. Unlike cochlear implantation, which circumvents damaged sensory structures, OTOF gene replacement targets a synaptic deficit in
Jazlyn A. Selvasingh, Justin R. Shinn
wiley +1 more source
A novel minimally invasive stereotaxic technique to target inner ear neurons in the mouse. [PDF]
Front NeurolAl-Asad RK, Luu NC, Edge AS, Kempfle JS.
europepmc +1 more source
The Audiologic and Otolaryngologic Phenotype in WHIM Syndrome
Otolaryngology–Head and Neck Surgery, EarlyView.Abstract Objective WHIM syndrome (warts, hypogammaglobulinemia, infections, and myelokathexis syndrome) is an ultra‐rare primary immunodeficiency disease caused by autosomal dominant hyperfunctional mutations in the chemokine receptor CXCR4. Otolaryngologists are frequently consulted to evaluate WHIM patients because of recurrent acute ear and sinus ...
Christopher K. Zalewski +7 more
wiley +1 more source
Cochlear implantation in children with congenital inner ear anomalies: challenges and outcomes. [PDF]
Eur Arch OtorhinolaryngolUrik M, Hosnova D, Kruntorad V, Sima J.
europepmc +1 more source
Molecular Biomarkers in Meniere's Disease: A Scoping Review of Current Evidence
Otolaryngology–Head and Neck Surgery, EarlyView.Abstract Objective Meniere's disease is a complex chronic inner ear condition that is characterized by vertigo, tinnitus, aural fullness, and progressive hearing loss. Currently, diagnostic strategies remain symptom‐driven, and treatments focus on management of discrete episodes rather than targeting underlying pathophysiology.
Hamza Kamran +3 more
wiley +1 more source
Deep Learning-Based Inner Ear Subregion Segmentation in 3D T2-Weighted MRI Using Label-Preserving Data Augmentation. [PDF]
NMR BiomedKim W, Kang Y, Lee S, Lee HJ, Nam Y.
europepmc +1 more source
Prenatal Diagnosis, EarlyView.ABSTRACT Objective To review the published literature on prenatal findings of COL2A1‐related SEDC, summarizing reported imaging and molecular variants, and to describe two additional prenatal cases evaluated at a tertiary referral center. Method A narrative review with a systematic search strategy was conducted to analyze prenatal imaging findings ...
López‐Rodríguez Larissa +10 more
wiley +1 more source