Results 31 to 40 of about 808,804 (186)

RAF kinase activity regulates neuroepithelial cell proliferation and neuronal progenitor cell differentiation during early inner ear development [PDF]

, 2010
Background: Early inner ear development requires the strict regulation of cell proliferation, survival, migration and differentiation, coordinated by the concerted action of extrinsic and intrinsic factors.
Rapp Ulf R., Marta Magariños, Varela-Nieto, Isabel, Hortensia Sánchez-Calderón, Aburto María R., Muñoz-Agudo, Carmen, Muñoz-Agudo Carmen, Rapp, Ulf Rüdiger, Rodriguez Aburto, Maria, María R. Aburto, Magariños Marta, María R Aburto, Sánchez-Calderón, Hortensia, Rapp, Ulf R., Ulf R Rapp, Isabel Varela-Nieto, Varela-Nieto Isabel, Magariños, Marta, Carmen Muñoz-Agudo, Sánchez-Calderón Hortensia, Ulf R. Rapp, Muñoz Agudo, Carmen   +21 more
core   +2 more sources

Genetic Causes of Sensorineural Hearing Loss Associated with Inner Ear Malformations

, 2022
Clinically significant hearing loss is present in ~1 per 500 newborns and affects more than 30% of the population at some time in their lives. Empowered by the astounding progress in DNA sequencing technology, recent studies have brought the number of ...
Tekin, Mustafa, Liu, Wenxin, Bademci, Guney, Ocak, Emre   +3 more
core   +1 more source

The effect of cochlear size on electrically evoked auditory brainstem responses in deaf children

Laryngoscope Investigative Otolaryngology, 2023
Objectives To investigate the relationship between auditory pathway function and cochlear size in deaf children with a radiologically normal inner ear or Mondini malformation.
Han‐Yu Zhu, Jia‐Qiang Sun, Jing‐Wu Sun, Xiao‐Tao Guo   +3 more
doaj   +1 more source

Clinical Review of Inner Ear Malformation

Nippon Jibiinkoka Gakkai Kaiho, 2003
We had 126 patients with inner ear malformation diagnosed with temporal bone computed tomography (CT) scans at Azabu Triology Hospital between 1996 and 2002. We classified cases of inner ear malformation according to Jackler et al. The incidence of inner ear malformation in our series was as follows; 1.
Kokai, Hiromi, Oohashi, Masami, Ishikawa, Kazuo, Harada, Kouji, Hiratsuka, Hitoshi, Ogasawara, Makoto, Miyashita, Souji, Terayama, Yoshihiko   +7 more
openaire   +3 more sources

Cystic Cochleovestibular Malformation (Incomplete Partition Type 1)

Philippine Journal of Otolaryngology Head and Neck Surgery, 2010
A 5-year old female with bilateral profound hearing loss underwent computerized tomographic imaging of the temporal bone as part of the work-up to determine the etiology of her deafness, and to delineate middle and inner ear anatomy prior to cochlear ...
Nathaniel W. Yang
doaj   +1 more source

A Model of Waardenburg Syndrome Using Patient-Derived iPSCs With a SOX10 Mutation Displays Compromised Maturation and Function of the Neural Crest That Involves Inner Ear Development

Frontiers in Cell and Developmental Biology, 2021
Waardenburg syndrome (WS) is an autosomal dominant inherited disorder that is characterized by sensorineural hearing loss and abnormal pigmentation. SOX10 is one of its main pathogenicity genes. The generation of patient-specific induced pluripotent stem
Jie Wen, Jie Wen, Jie Wen, Jian Song, Jian Song, Jian Song, Yijiang Bai, Yijiang Bai, Yijiang Bai, Yalan Liu, Yalan Liu, Yalan Liu, Xinzhang Cai, Xinzhang Cai, Xinzhang Cai, Lingyun Mei, Lingyun Mei, Lingyun Mei, Lu Ma, Chufeng He, Chufeng He, Chufeng He, Yong Feng, Yong Feng   +23 more
doaj   +1 more source

Characterization of the Usher Syndrome gene CDH23: implications for mechanosensation in the vertebrate inner ear [PDF]

, 2004
Deafness is the most common form of sensory impairment afflicting the human population. Approximately one in eight hundred children is born with serious hearing impairment and more than half of these cases are likely due to single gene defects.
Siemens, Jan-Erik
core   +1 more source

Molecular Etiology of Hearing Impairment in Inner Mongolia: mutations in SLC26A4 gene and relevant phenotype analysis

Journal of Translational Medicine, 2008
Background The molecular etiology of hearing impairment in Chinese has not been thoroughly investigated. Study of GJB2 gene revealed that 30.4% of the patients with hearing loss in Inner Mongolia carried GJB2 mutations.
Wu Bailin, Yuan Huijun, Kang Dongyang, Yu Fei, Zhu Xiuhui, Huang Deliang, Yuan Yongyi, Dai Pu, Han Dongyi, Wong Lee-Jun C   +9 more
doaj   +1 more source

Molecular biology of hearing [PDF]

, 2012
The inner ear is our most sensitive sensory organ and can be subdivided into three functional units: organ of Corti, stria vascularis and spiral ganglion.
Diensthuber, M, Stöver, T, Diensthuber, Marc, Stöver, Timo   +3 more
core   +1 more source

Evaluation of cochlear implantation in children with inner ear malformation

B-ENT, 2014
Evaluation of cochlear implantation in children with inner ear malformation. Objective: This study aimed to compare the outcomes of cochlear implantation (CI) in children with malformed versus normal inner ear anatomy.
H. Zhou, X. Sun, Z. Chen, H. Shi, Y. Wu, W. Zhang, S. Yin   +6 more
doaj   +2 more sources