Results 1 to 10 of about 212,057 (189)

The mycotoxin phomoxanthone A disturbs the form and function of the inner mitochondrial membrane. [PDF]

Cell Death Dis, 2018
Mitochondria are cellular organelles with crucial functions in the generation and distribution of ATP, the buffering of cytosolic Ca2+ and the initiation of apoptosis. Compounds that interfere with these functions are termed mitochondrial toxins, many of
Böhler P, Stuhldreier F, Anand R, Kondadi AK, Schlütermann D, Berleth N, Deitersen J, Wallot-Hieke N, Wu W, Frank M, Niemann H, Wesbuer E, Barbian A, Luyten T, Parys JB, Weidtkamp-Peters S, Borchardt A, Reichert AS, Peña-Blanco A, García-Sáez AJ, Itskanov S, van der Bliek AM, Proksch P, Wesselborg S, Stork B.   +24 more
europepmc   +6 more sources

Absence of Cardiolipin From the Outer Leaflet of a Mitochondrial Inner Membrane Mimic Restricts Opa1-Mediated Fusion [PDF]

Frontiers in Molecular Biosciences, 2021
Cardiolipin is a tetra-acylated di-phosphatidylglycerol lipid enriched in the matrix-facing (inner) leaflet of the mitochondrial inner membrane. Cardiolipin plays an important role in regulating mitochondria function and dynamics.
Yifan Ge, Yifan Ge, Sivakumar Boopathy, Sivakumar Boopathy, Tran H. Nguyen, Tran H. Nguyen, Camila Makhlouta Lugo, Camila Makhlouta Lugo, Luke H. Chao, Luke H. Chao   +9 more
doaj   +2 more sources

Examination of bioenergetic function in the inner mitochondrial membrane peptidase 2-like (Immp2l) mutant mice

Redox Biology, 2014
Inner mitochondrial membrane peptidase 2-like (IMMP2L) protein is a mitochondrial inner membrane peptidase that cleaves the signal peptide sequences of cytochrome c1 (CYC1) and mitochondrial glycerol phosphate dehydrogenase (GPD2).
Manish S. Bharadwaj, Yu Zhou, Anthony J. Molina, Tracy Criswell, Baisong Lu   +4 more
doaj   +2 more sources

SLMO transfers phosphatidylserine between the outer and inner mitochondrial membrane in Drosophila. [PDF]

PLoS Biology
Phospholipids are critical building blocks of mitochondria, and proper mitochondrial function and architecture rely on phospholipids that are primarily transported from the endoplasmic reticulum (ER).
Siwen Zhao, Xuguang Jiang, Ning Li, Tao Wang   +3 more
doaj   +2 more sources

Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor. [PDF]

Cell, 2017
Wei Y, Chiang WC, Sumpter R, Mishra P, Levine B.   +4 more
europepmc   +3 more sources

Cardiolipin remodeling maintains the inner mitochondrial membrane in cells with saturated lipidomes. [PDF]

J Lipid Res
Venkatraman K, Budin I.
europepmc   +3 more sources

Exposure of the inner mitochondrial membrane triggers apoptotic mitophagy. [PDF]

Cell Death Differ
Saunders TL, Windley SP, Gervinskas G, Balka KR, Rowe C, Lane R, Tailler M, Nguyen TN, Ramm G, Lazarou M, De Nardo D, Kile BT, McArthur K.   +12 more
europepmc   +3 more sources

Targeting and Insertion of Membrane Proteins in Mitochondria

Frontiers in Cell and Developmental Biology, 2021
Mitochondrial membrane proteins play an essential role in all major mitochondrial functions. The respiratory complexes of the inner membrane are key for the generation of energy. The carrier proteins for the influx/efflux of essential metabolites to/from
Ross Eaglesfield, Kostas Tokatlidis
doaj   +1 more source

Pathways shaping the mitochondrial inner membrane

Open Biology, 2021
Mitochondria are complex organelles with two membranes. Their architecture is determined by characteristic folds of the inner membrane, termed cristae.
Till Klecker, Benedikt Westermann
doaj   +1 more source

Mitochondrial DNA mutations provoke dominant inhibition of mitochondrial inner membrane fusion. [PDF]

PLoS ONE, 2012
Mitochondria are highly dynamic organelles that continuously move, fuse and divide. Mitochondrial dynamics modulate overall mitochondrial morphology and are essential for the proper function, maintenance and transmission of mitochondria and mitochondrial
Cécile Sauvanet, Stéphane Duvezin-Caubet, Bénédicte Salin, Claudine David, Aurélie Massoni-Laporte, Jean-Paul di Rago, Manuel Rojo   +6 more
doaj   +1 more source