Results 171 to 180 of about 212,226 (348)

Bone Organoids: A Novel Tool for Modeling and Managing Skeletal Disorders in Diabetes

open access: yesAdvanced Science, EarlyView.
This review synthesizes advances in bone organoid engineering and evaluates their potential to model diabetic bone fragility. Current in vitro and animal models do not fully recapitulate diabetes‐associated skeletal phenotypes. Cell‐based and scaffold‐based bone organoids are discussed as complementary approaches to reconstruct multicellular bone ...
Shuangzhe Lin   +2 more
wiley   +1 more source

Author response: Two forms of Opa1 cooperate to complete fusion of the mitochondrial inner-membrane

open access: gold, 2019
Yifan Ge   +5 more
openalex   +1 more source

Nature‐Inspired Surface Modification Strategy Reverses the Autophagic Flux Impairment of Mitochondrial Transplantation for Attenuating Ischemic Strokes

open access: yesAdvanced Science, EarlyView.
The functionalized starch modifies the mitochondrial surface and encapsulates resveratrol into the cavity of helices, facilitating a novel mitochondrial transplantation platform (MLSR). Upon internalization in recipient cells, MLSR triggers mitophagy and maintains positive autophagic flux through RIP1/RIP3 pathway inhibition.
Nisha Wang   +12 more
wiley   +1 more source

Destabilization of the Outer and Inner Mitochondrial Membranes by Core and Linker Histones

open access: gold, 2012
Annunziata Cascone   +4 more
openalex   +2 more sources

Mic10 Oligomerizes to Bend Mitochondrial Inner Membranes at Cristae Junctions [PDF]

open access: bronze, 2015
Mariam Barbot   +7 more
openalex   +1 more source

MICOS assembly controls mitochondrial inner membrane remodeling and crista junction redistribution to mediate cristae formation [PDF]

open access: hybrid, 2020
Till Stephan   +19 more
openalex   +1 more source

PAF Triggered Pyroptotic NETosis Aggravates Myocardial Ischemia/Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
Platelet activating factor (PAF) secreted by cardiomyocytes during MI/R, drives NETs formation and subsequent NETosis. PAF/NETosis signaling activation is an initiative and causal factor in driving MI/R injury. This study identifies dapagliflozin as a potent NETosis inhibitor, and demonstrates that manipulating PAF‐NETosis signal by dapagliflozin or ...
Jiawei Wu   +11 more
wiley   +1 more source

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