Results 61 to 70 of about 319,939 (295)

Numerical Investigation of Convection and Radiation Heat Loss Reduction between Two Finite Concentric Cylinders Using Radiation Shields [PDF]

open access: yesمجله مدل سازی در مهندسی, 2017
Investigation of the radiation and natural convection heat losses from two finite concentric cylinders with radiation shields is performed numerically.
Seyfolah Saedodin   +1 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Optimal design of a flying-wing aircraft inner wing structure configuration [PDF]

open access: yes, 2012
Flying-wing aircraft are considered to have great advantages and potentials in aerodynamic performance and weight saving. However, they also have many challenges in design.
Huang, Haidong
core  

The Programming of Parameters Influencing the Index of Performance for Large Tires of Great Dimension in the Conditions of Real Exploitation

open access: yesМеханика машин, механизмов и материалов, 2015
A programme is developed and tested that allows to determine automatically recommended parameters of temperature and inside pressure in the tyre by the way of changing speed and the load on the wheel in field tests with the help of the lap top.
Sergei I. Medveditskov   +2 more
doaj  

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

Design of high-temperature superconductors at moderate pressures by alloying AlH3 or GaH3

open access: yesMatter and Radiation at Extremes
Since the discovery of hydride superconductors, a significant challenge has been to reduce the pressure required for their stabilization. In this context, we propose that alloying could be an effective strategy to achieve this.
Xiaowei Liang   +6 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Investigation of Pressure and Pressure Gradients along the LA/TX Inner Shelf and their Relationships to Wind Forcing and Current Variability [PDF]

open access: yes, 2001
Summary describing the work completed at Louisiana State University (Baton Rouge, La.). Coastal Studies Institute. for Pressure Gauge and Moored CTD Array along the Louisiana Coastal Current.
Louisiana State University (Baton Rouge, La.). Coastal Studies Institute.
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Surface effects in flow boiling of R134a in microtubes

open access: yes, 2011
This is the post-print version of the Article. The official published version can be accessed from the link below - Copyright @ 2011 ElsevierThe inner surfaces of microtubes may be influenced strongly by the process of making them due to manufacturing ...
Tassos G. Karayiannis   +5 more
core   +1 more source

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