Results 51 to 60 of about 6,970,988 (348)

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Meta-Analysis: Randomized Trials of Lactobacillus plantarum on Immune Regulation Over the Last Decades

open access: yesFrontiers in Immunology, 2021
Lactobacillus (L.) plantarum strains, belong to lactic acid bacteria group, are considered indispensable probiotics. Here, we performed meta-analysis to evaluate the regulatory effects of L. plantarum on the immunity during clinical trials.
Wei Zhao   +15 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Design of Primers for Evaluation of Lactic Acid Bacteria Populations in Complex Biological Samples

open access: yesFrontiers in Microbiology, 2018
Lactic acid bacteria (LAB) are important for human health. However, the relative abundance of LAB in complex samples, such as fecal samples, is low and their presence and diversity (at the species level) is understudied.
Qiangchuan Hou   +13 more
doaj   +1 more source

Edge-state inner products and real-space entanglement spectrum of trial quantum Hall states [PDF]

open access: yes, 2012
We consider the trial wavefunctions for the Fractional Quantum Hall Effect (FQHE) that are given by conformal blocks, and construct their associated edge excited states in full generality.
J. Dubail, N. Read, E. Rezayi
semanticscholar   +1 more source

Sharp Inequalities of Ostrowski Type for Convex Functions Defined on Linear Spaces and Application

open access: yes, 2007
An Ostrowski type inequality for convex functions defined on linear spaces is generalised. Some inequalities which improve the Hermite–Hadamard type inequality for convex functions defined on linear spaces are derived using the obtained result.
Cerone, P.   +4 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Temperature-dependent metabolic interactions between Streptococcus thermophilus and Lactobacillus delbrueckii ssp. bulgaricus in milk fermentation: Insights from gas chromatography–ion mobility spectrometry metabolomics

open access: yesJournal of Dairy Science
: Streptococcus (S.) thermophilus and Lactobacillus (L.) delbrueckii ssp. bulgaricus are widely used as a combined starter culture for milk fermentation, often at temperatures of 37°C and 42°C.
Ting Wu   +4 more
doaj   +1 more source

Comparison of Bacterial Microbiota in Raw Mare’s Milk and Koumiss Using PacBio Single Molecule Real-Time Sequencing Technology

open access: yesFrontiers in Microbiology, 2020
Koumiss is a traditional fermented raw mare’s milk product. It contains high nutritional value and is well-known for its health-promoting effect as an alimentary supplement.
Meng Zhang   +26 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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