Results 71 to 80 of about 2,914 (165)

CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems

The FEBS Journal, EarlyView.
Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén, Viktória Varga, Fatime Szalai, Risa Miyaura, Nóra Förhécz, Bálint Csikós, Rebeka Gelencsér, Zsófia Gábriel, Timea Komlódi, Katalin Dezső, Ildikó Krencz, Dorottya Moldvai   +11 more
wiley   +1 more source

A LEADER program szerepe a helyi önkormányzatok nemzetközi együttműködésének támogatásában

Tér és Társadalom
Az Európai Unióban a több, mint három évtizedes múltra visszatekintő LEADER program mindmáig egy olyan sajátos fejlesztési módszer, amelyben a place-based (helyalapú), alulról felfele építkező szemlélet a vállalkozások és civil szervezetek mellett a ...
István Finta
doaj   +1 more source

Tankyrase‐2 regulates adipocyte differentiation through AMPK/mTOR signaling

The FEBS Journal, EarlyView.
Tankyrase 2 (TNKS2), a PARP family member, underpins adipocyte differentiation. TNKS2 controls LKB1 protein level, and consequently, the activity of the mTOR/AMPK system and adipocyte differentiation through a layered process. Pharmacological inhibition of TNKS2 leaves other PARPs and DNA repair active and therefore represents a novel target in ...
Boglarka Rauch, Gyula Ujlaki, Szilard Poliska, Nakayi Murahwa, Patrik Kovacs, Aladar Pettko‐Szandtner, Karen Uray, Peter Bai   +7 more
wiley   +1 more source

Dissenyant la innovació

Temes de Disseny, 2006
La prominència creixent del disseny ha fet que cada vegada es presti més atenció als nous mètodes i estratègies per aconseguir innovació, tant en el món professional com en l'ensenyament del disseny.
Mark Breitenberg
doaj  

Risk Factors and Clinical Severity in Chronic Venous Disease: A New Look

International Journal of Dermatology, EarlyView.
Genetic factors, such as gender and positive family history, were associated with the occurrence of mild‐stage disease (CEAP C1–3). Obesity, lack of exercise, and working more than 8 h in a sitting or standing position are strongly associated with severe venous disease (CEAP C4–6).
Éva Badak, Eszter A. Janka, Patrícia Ari, Edina Bodnár, Krisztina Varga, László Virág, Éva Szabó   +6 more
wiley   +1 more source

How to optimise tournament draws: The case of the FIFA World Cup

International Transactions in Operational Research, EarlyView.
Abstract The organisers of major sports competitions use different policies with respect to constraints in the group draw. Our paper aims to rationalise these choices by analysing the trade‐off between attractiveness (the number of games played by teams from the same geographic zone) and fairness (the departure of the draw mechanism from a uniform ...
László Csató
wiley   +1 more source

Lower density of calretinin‐immunopositive neurons in the putamen of subjects with schizophrenia

Journal of Anatomy, Volume 246, Issue 4, Page 505-516, April 2025.
Recent neuroimaging and histological studies highlight the striatum as a key area involved in SCH, but the specific impairment of neuronal subtypes in subcortical structures is not fully understood. This study is the first detailed investigation of neuroanatomical changes in the putamen in SCH, specifically examining the density of calretinin ...
Paz Kelmer, Paulina Hoppa, Erzsébet Frank, Teadora Tyler, Istvan Adorjan   +4 more
wiley   +1 more source

The Experience of Care in People With Palliative Needs and Their Families: A Qualitative Metasynthesis

Journal of Clinical Nursing, EarlyView.
ABSTRACT Aim To synthesise and reinterpret qualitative evidence on how people with palliative care needs and their family caregivers experience the care process. Background Palliative care aims to provide holistic, person‐ and family‐centred care.
Ana Gil Méndez, Caterina Checa Jiménez, Ingrid Bullich Marín, Laura Navarrete Reyes, Carolina Watson Badia, Nina Granel Gimenez, Lídia Ribera Barberan, Mireia Subirana Casacuberta, Juan M. Leyva‐Moral   +8 more
wiley   +1 more source

The ultrarapid delayed rectifier potassium current has important functional role in the repolarization reserve of canine and human ventricular muscle

The Journal of Physiology, EarlyView.
Abstract figure legend The ultrarapid delayed rectifier potassium current (IKur) has long been considered an atrial‐specific current with no functional role in the ventricles, despite evidence of its expression in ventricular myocytes. In the present study we challenged this prevailing concept and investigated the potential role of IKur in ventricular ...
Alaa Amin E. Abdelmagid, Aiman Saleh A. Mohammed, Gábor Mohácsi, Benjámin Paskuj, Gergő Bitay, Jakub Tomek, Sahil Dalal, Tamás Árpádffy‐Lovas, Vivien Demeter‐Haludka, István Koncz, Muhammad Naveed, László Virág, Norbert Nagy, András Varró, István Baczkó, Norbert Jost, Zsófia Kohajda, Leila Topal   +17 more
wiley   +1 more source

A Super‐Resolution Approach for Astrocyte‐Specific Molecular Imaging Reveals the Nanoscale Distribution of Monoacylglycerol Lipase, the Metabolic Node Between Endocannabinoid and Prostaglandin Signaling

Glia, Volume 74, Issue 9, September 2026.
Dual‐color STORM resolves the precise architecture and protein distributions within hippocampal astrocytes at the nanoscale. Identification of a sparse but specific MAGL pool in CA1 astrocytic processes. Astrocytic MAGL is not synapse‐associated, suggesting a synapse‐independent role.
Miklós Zöldi, István Katona
wiley   +1 more source