Results 71 to 80 of about 2,891,562 (358)
National Systems of Innovation : Towards a Theory of Innovation and Interactive Learning
, 2012 Introduction Theories in the social sciences may be regarded as ‘focusing devices’. Any specific theory brings forward and exposes some aspects of the real world, leaving others in obscurity.
B. Lundvall
semanticscholar +1 more source
Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source
Innovation for equity in Lebanon
Forced Migration Review, 2014 Innovative approaches in Lebanon aim to address, in two very different ways, the particular needs of the most vulnerable among the refugee and host populations.
Luciano Calestini
doaj
PLoS ONE, 2020 This study aims to explore the direct effect and spillover effect of innovation policy in the distribution and dynamic evolution of the regional innovation from the perspective of innovation motivation using the spatial econometric model.
Yanyang Yan, Zhichao Wu
doaj +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Humanitarian innovation, humanitarian renewal?
Forced Migration Review, 2014 The continued evolution of the humanitarian innovation concept needs a critical engagement with how this agenda interacts with previous and contemporary attempts to improve humanitarian action.
Kristin Bergtora Sandvik
doaj
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
UNHCR Ideas: an online platform for change
Forced Migration Review, 2014 ‘UNHCR Ideas’ aims to enable collaborative problem solving and idea generation among an online community.
Alice Bosley
doaj
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Technology, production and partnership innovation in Uganda
Forced Migration Review, 2014 Since 2007 a partnership between UNHCR, the Government of Uganda and ‘MakaPads’ inventor Moses Musaazi has helped provide affordable sanitary pads for thousands of refugee girls and women while substantially reducing UNHCR’s expenditure on these ...
Moses Musaazi
doaj