Results 71 to 80 of about 5,711,473 (427)
CRIBs (Climate Relevant Innovation-system Builders): policy recommendations on fostering national systems of innovation under the UNFCCC [PDF]
, 2014 National systems of innovation (NSIs) provide the context within which all processes of technology development, transfer and uptake occur - they refer to the network of actors (e.g.
Byrne, Robert, Ockwell, David
core
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Enterprise System Lifecycle-wide Innovation [PDF]
arXiv, 2020 Enterprise Systems purport to bring innovation to organizations. Yet, no past studies, neither from innovation nor from ES disciplines have merged their knowledge to understand how ES could facilitate lifecycle-wide innovation. Therefore, this study forms conceptual bridge between the two disciplines.
arxiv
The Beneficial Role of Mobility for the Emergence of Innovation [PDF]
Scientific Reports 7, Article number: 1781 (2017), 2017 Innovation is a key ingredient for the evolution of several systems, including social and biological ones. Focused investigations and lateral thinking may lead to innovation, as well as serendipity and other random discovery processes. Some individuals are talented at proposing innovation (say innovators), while others at deeply exploring proposed ...
arxiv +1 more source
Central problems in the management of innovation
, 1986 Innovation is defined as the development and implementation of new ideas by people who over time engage in transactions with others within an institutional order.
A. Ven
semanticscholar +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
Primary extranodal diffuse large B‐cell lymphoma: Molecular features, treatment, and prognosis
Aging and Cancer, Volume 3, Issue 3-4, Page 133-146, September-December 2022., 2022 One‐third of DLBCL arises from extranodal organs and is challenging to manage. Molecular features are critical to elucidate the differences in clinical features, predict the disease prognosis, and improve effective targeted therapeutic strategies. Abstract Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of non‐Hodgkin's lymphoma and ...
Si‐Yuan Chen +3 more
wiley +1 more source
An Integrated Model for User Innovation Knowledge Based on Super-network [PDF]
arXiv, 2019 Online user innovation communities are becoming a promising source of user innovation knowledge and creative users. With the purpose of identifying valuable innovation knowledge and users, this study constructs an integrated super-network model, i.e., User Innovation Knowledge Super-Network (UIKSN), to integrate fragmented knowledge, knowledge fields ...
arxiv
Innovation Diffusion among Case-based Decision-makers [PDF]
arXiv, 2022 This paper analyzes a model of innovation diffusion with case-based individuals a la Gilboa and Schmeidler (1995,1996,1997), who decide whether to consume an incumbent or a new product based on their and their social neighbors' previous consumption experiences.
arxiv