Results 101 to 110 of about 5,275,403 (305)

Labour productivity among small- and medium-scale enterprises in Uganda: the role of innovation

Journal of Innovation and Entrepreneurship, 2018
Using the 2013 World Bank Enterprise Survey data for Uganda, this paper employs the quintile estimation technique to explain the relationship between labour productivity and innovation among SMEs.
Ibrahim Mike Okumu, Faisal Buyinza
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Experience, Innovation and Productivity - Empirical Evidence from Italy's Slowdown [PDF]

We investigate the role of workers’ and managerial experience as a determinant of firm innovation and productivity in a sample of Italian manufacturing firms.
Maria Laura Parisi, Francesco Daveri
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Innovation, productivity and export Evidence from Italy [PDF]

Recent developments in the new international trade theory stressed the relationship between firm heterogeneity and internationalization performance. The key prediction of these models is that firms with different levels of productivity - the main source ...
Roberto Antonietti, Giulio Cainelli
core  

Executive Green Perception and Green Innovation Improve New Quality Productivity in Chinese Listed Firms

International Journal of Financial Studies
This research focuses on Chinese listed companies to explore the influence of green-oriented strategies and green innovation on corporate productivity.
Jiaran Li, Haslindar Ibrahim
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Innovation and productivity in SMEs. Empirical evidence for Italy [PDF]

Innovation in SMEs exhibits some peculiar features that most traditional indicators of innovation activity do not capture. Therefore, in this paper, we develop a structural model of innovation which incorporates information on innovation success from ...
Bronwyn H. Hall, Jacques Mairesse, Francesca Lotti   +2 more
core  

Factors Influencing Innovation Management in Iraq’s Small- and Medium-sized Enterprises

Cihan University-Erbil Journal of Humanities and Social Sciences
By adopting technology, enhancing productivity, and fostering economic growth in small and medium-sized enterprises (SMEs), owners and managers can improve their innovation management methods. Owners and managers can optimize their innovation management
Muslim N. Zaidan, Sameer S. Hamdi, Hawkar Q. Birdawod, Azwar M.Q. Agha   +3 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source