Results 111 to 120 of about 5,275,403 (305)
Innovation, R&D Investment and Productivity: Uruguayan Manufacturing Firms [PDF]
Uruguay’s inability to sustain high levels of economic growth cannot be fully explained by external shocks, the prevailing institutional setting or the level of human capital accumulation.
Adriana Cassoni, Magdalena Ramada
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Innovation and Productivity a Story of Convergence and Divergence Process in EU Countries [PDF]
Technology is apparently one of the main determining sources of productivity and economic growth and there is a huge literature on productivity, growth and innovation.
Aikaterini Kokkinou
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Telecommunications productivity, catch-up and innovation [PDF]
This study examines telecommunications productivity, technological catch-up and innovation in 74 countries for the period 1991-1995. A summary of partial productivity indicators is presented, and total factor productivity (TFP) growth is calculated using
Savage, Scott J, Madden, Gary G
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Digital transformation, eco-innovation and total factor productivity in Spanish manufacturing firms
Cogent Business & ManagementDigital transformation and sustainability-oriented practices are reshaping the competitive dynamics of manufacturing firms, yet their joint implications for productivity remain insufficiently understood.
Albert Miró-Pérez +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
The impact of innovation activities on productivity and firm growth: evidence from Brazil [PDF]
Using micro data from Brazilian manufacturing firms, this paper investigates the impact of a wide set of innovation activities on firms' total factor productivity (TFP) and its subsequent effect on firm growth, measured by sales. Controlling for size and
Goedhuys, Micheline
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Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
How does competition affect the relationship between innovation and productivity? Estimation of a CDM model for Norway [PDF]
The paper investigates the effects of industry-level competition on firm-level innovation and productivity. We propose a refined version of the CDM model that analyses the impacts of competition on four interrelated stages of the innovation process: the ...
Castellacci, Fulvio
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