Results 51 to 60 of about 117,222 (307)

Productivity, Smart Specialisation, and Innovation:

open access: yesREGION, 2023
The paper aims to enrich the discussion on the Research and Innovation Strategies for Smart Specialisation (RIS3) and ongoing development of macro-regions in the EU.
Mirko Kruse   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Product Innovation Influence on Production Organization

open access: yes, 2018
This article deals with individual product innovations and their influence on production workplace and the technological production process. This work firstly deals with the current scientific knowledge, followed by the research itself, which defines the individuals inputs - product innovations and then the individual links between these innovations ...
Polášek, Patrik, Šimon, Michal
openaire   +2 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Analysis of the Spatial Pattern of Innovation-Driven Productivity at the Intra-Urban Scale in a Megacity Based on Multi-Source Data: A Case Study for Shanghai

open access: yesLand
In the context of accelerating technological and industrial transformation, innovation-driven productivity has garnered significant attention. Based on multi-source data, this study employs the entropy method and spatial pattern analysis to delve into ...
Donghui Shi
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

INNOVATION PRODUCTION MODELS

open access: yesMGIMO Review of International Relations, 2016
The article is dedicated to the study of the models of production of innovations at enterprise and state levels. The shift towards a new technology wave induces a change in systems of division of labour as well as establishment of new forms of cooperation that are reflected both in theory and practice of innovation policy and management.
openaire   +5 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Product, Process and Organizational Innovation: Drivers, Complementarity and Productivity Effects [PDF]

open access: yes
We propose a model where both R&D and ICT investment feed into a system of three innovation output equations (product, process and organizational innovation), which ultimately feeds into a productivity equation.
Wladimir Raymond   +3 more
core   +2 more sources

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