Results 61 to 70 of about 117,222 (307)

Firm Productivity and Type of Innovation: Evidence from the Community Innovation Survey 6

Croatian Economic Survey, 2014
Having recognized the impact of innovation for the improvement of productivity in firms and for the growth of national economies, researchers have been exploring the innovation process and its underlying factors for over a decade now.
Nebojša Stojčić, Iraj Hashi
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Mathematical Optimization in Innovation Productivity: A Framework and A Case Study on UAV Border Patrolling in Türkiye

Verimlilik Dergisi
Purpose: In this paper, the potential of mathematical optimization (MO) in enhancing innovation productivity is explored. Innovation is a process that converts new ideas and methods into products and services, MO can contribute to innovation management ...
Erdi Daşdemir
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

The effects of entry on incumbent innovation and productivity [PDF]

, 2009
How does firm entry affect innovation incentives in incumbent firms? Microdata suggest that there is heterogeneity across industries. Specifically, incumbent productivity growth and patenting is positively correlated with lagged greenfield foreign firm ...
Rachel, Griffith, Richard Blundell, Susanne, Prantl, Blundell, Richard, Howitt, Peter, Rachel Griffith, Aghion, Philippe, Richard, Blundell, Blundell, R., Griffith, R., Peter Howitt, Philippe Aghion, Peter, Howitt, Prantl, S., Susanne Prantl, Prantl, Susanne, Griffith, Rachel; id_orcid, Aghion, P., Howitt, P.   +18 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

The Path of Smart Agricultural Technology Innovation Leading Development of Agricultural New Quality Productivity

智慧农业
SignificanceBuilding the agricultural new quality productivity is of great significance. It is the advanced quality productivity which realizes the transformation, upgrading, and deep integration of substantive, penetrating, operational, and media ...
CAO Bingxue, LI Hongfei, ZHAO Chunjiang, LI Jin   +3 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

How Does Government Attention Enhance Regional Innovation Performance From the Perspective of Innovation-driven Productivity?

SAGE Open
The concept of innovation-driven productivity is a crucial factor in fostering high-quality economic development, grounded in economic theories and practices from the past several decades.
Sheng Chen, Heng Yang, Jie Li
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source