Results 51 to 60 of about 557,025 (268)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Crossing the digital frontier: are older adults ready for virtual reality workouts?

Frontiers in Public Health
In the dynamic web of our digital age, virtual reality (VR) is crystallizing as a promising medium for promoting physical activity in older adults, overcoming age-old barriers.
André Ramalho, André Ramalho, Pedro Duarte-Mendes, Pedro Duarte-Mendes, Rui Paulo, Rui Paulo, João Serrano, João Serrano, João Petrica, João Petrica   +9 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Relationship between bioelectrical impedance–derived muscle quality and physical activity, sedentary behavior, or sleep using compositional data analysis (CoDA)

Scientific Reports
The association between exercise behaviors—including physical activity (PA), light-intensity PA (LPA), moderate-to-vigorous-intensity PA (MVPA), sedentary behavior (SB), and sleep—and muscle quality remains unclear.
Yujiro Asano, Motohiko Miyachi, Hinako Nanri, Haruka Murakami, Yuko Gando, Takashi Nakagata, Tsukasa Yoshida, Tomohiro Okura, Yosuke Yamada   +8 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

THE SYSTEM OF INNOVATION ENVIRONMENT MANAGEMENT: REGIONAL ASPECT

Вестник Российского экономического университета имени Г. В. Плеханова, 2018
The article describes ways of calculating economic efficiency of innovation. It shows parameters characterizing the level of innovation activity development at the present stage.
Aleksandr A. Gretchenko, Olga G. Demenko, Irina V. Gorokhova   +2 more
doaj   +1 more source

The problems of innovative activity activization

Экономический вестник Донбасса, 2016
Methods of innovation activization have been considered in the article with the purpose of ensuring the competitiveness of the economy of Ukraine. The state of innovation development of industrial production in Ukraine and the Donetsk region have been analyzed. The determinative value of labor factor in the innovation organization has been showed.
VETSEPURA N., PROKOFIEVA S.
openaire   +2 more sources

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

(Dis)satisfaction With Body Image, Lifestyles and Life Satisfaction in Higher Education Students

Revista de Investigación e Innovación en Ciencias de la Salud
Objective. Body image is a predictor of physical, psychological, and social health. Therefore, it can be an indicator for detecting health problems, to be used in the context of higher education.
Helena Ferreira-Barbosa, Vânia Loureiro, Bebiana Sabino   +2 more
doaj   +1 more source

Activity Of Companies In Innovation Networks

Equilibrium, 2012
Innovation networks can be understood as an organization in which two or more independent firms aim at joint research, development or spreading of innovations. In such a relatively stable and cooperative collaboration, the partner firms find support during one or more activities of the innovation process, which may increase their innovation performance
openaire   +2 more sources