Results 51 to 60 of about 124,389 (260)

BIM adoption within Australian Small and Medium-sized Enterprises (SMEs): an innovation diffusion model

open access: yesConstruction Economics and Building, 2016
Despite the envisaged benefits of BIM adoption for SMEs, BIM in SMEs has remained an underrepresented area within the available academic literature. This study proposes and draws upon a framework grounded on innovation diffusion theory (IDT) to provide ...
M. Reza Hosseini   +6 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Structural and diffusion effects in the Dutch fertility transition, 1870-1940

open access: yesDemographic Research, 2014
Background: Ever since the Princeton European Fertility Project, structural and diffusion effects on fertility behavior have been juxtaposed. However, we still hardly know what the relative effects were of shifting socio-economic conditions and shifts in
Hilde Bras
doaj   +1 more source

The Diffusion of Innovations in Social Networks [PDF]

open access: yes, 2005
AbstractThis chapter examines the effects of network topology on the diffusion of behaviors. A key empirical question is, what is the expected length of time for a network to “switch over” from the old behavior to the new? It uncovers conditions on network topology the decision process that, surprisingly, bound the expected waiting time for diffusion ...
openaire   +3 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

A Multiplex Network Perspective of Innovation Diffusion: An Information-Behavior Framework

open access: yesIEEE Access, 2020
Information transmission of innovation and peer effect among firms have significant impacts on innovation adoption decisions of firms, but those effects usually depend on the different types of inter-firm networks. Therefore, the diffusion of innovation (
Qian Yu, Zhehao Yu, Ding Ma
doaj   +1 more source

Impacts of Individual Innovativeness on the Acceptance of IT-based Innovations in Health Care Fields [PDF]

open access: yesHealthcare Informatics Research, 2010
ObjectivesThe purpose of this study is to identify the role of individual innovation to demographic variables for determining IT adoption behaviors. This study also examines the effect of individual innovation on IT adoption behaviors across IT types ...
Jae Sung Park, Hye Sook Kim
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan   +14 more
wiley   +1 more source

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