Results 31 to 40 of about 124,389 (260)

A Dynamical Innovation Diffusion Model with Fuzzy Coefficient and Its Application to Local Telephone Diffusion in China

open access: yesDiscrete Dynamics in Nature and Society, 2013
This paper studies the innovation diffusion problem with the affection of urbanization, proposing a dynamical innovation diffusion model with fuzzy coefficient, and uses the shifting rate of people from rural areas stepping into urban areas to show the ...
Zhigao Liao, Jiuping Xu, Liming Yao
doaj   +1 more source

Difusão de práticas sociais sustentáveis em nichos de inovação social de base: o caso do movimento das ecovilas

open access: yesDesenvolvimento e Meio Ambiente, 2016
This essay analyzes the processes of innovation and diffusion of sustainable social practices in grassroots innovation niches. To do so, it brings elements from social practice theory (SPT), which offers a new perspective on the understanding of the ...
Rebeca Roysen, Frédéric Mertens
doaj   +1 more source

Dynamic analysis and optimal control of knowledge diffusion model in regional innovation ecosystem under digitalization

open access: yesScientific Reports
Knowledge diffusion in regional innovation ecosystems is an important factor that influences the regional innovation efficiency. In regional innovation ecosystems under digital empowerment, the knowledge diffusion enables the optimal allocation of ...
Zitong He   +4 more
doaj   +1 more source

Infant Embryonal CNS Tumors: Molecular Insights and Treatment Considerations for Contemporary Pediatric Neuro‐Oncology

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan   +3 more
wiley   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

A Biologically Inspired Model of Distributed Online Communication Supporting Efficient Search and Diffusion of Innovation [PDF]

open access: yesInterdisciplinary Description of Complex Systems, 2016
We inhabit a world that is not only “small” but supports efficient decentralized search – an individual using local information can establish a line of communication with another completely unknown individual.
Soumya Baneerjee
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Innovation Toilet and Barriers of Diffusion in Developing Country Case Study: TOTO Electronic Bidet Seat Toilet

open access: yesAsian Journal of Technology Management, 2012
The innovation of electronic bidet seat toilet in Japan has diffused to more than sixty percent of Japanese household while it has low rate of diffusion in other countries especially in developing country.
Akbar Adhiutama   +2 more
doaj   +2 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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