Results 31 to 40 of about 3,526,717 (341)

A web of stakeholders and strategies: A case of broadband diffusion in South Korea [PDF]

open access: yes, 2003
When a new technology is launched, its diffusion becomes an issue of importance. There are various stakeholders that influence diffusion. The question that remains to be determined is their identification and roles. This paper outlines how the strategies
Damsgaard J.   +19 more
core   +2 more sources

Dynamic analysis and optimal control of knowledge diffusion model in regional innovation ecosystem under digitalization

open access: yesScientific Reports
Knowledge diffusion in regional innovation ecosystems is an important factor that influences the regional innovation efficiency. In regional innovation ecosystems under digital empowerment, the knowledge diffusion enables the optimal allocation of ...
Zitong He   +4 more
doaj   +1 more source

Complex Dynamics of Innovation Diffusion [PDF]

open access: yesProblemi Ekonomiki
To search for innovative ways of sustainable growth within the trend of global economic expansion, it is necessary to have formalized approaches within the framework of the synergetic paradigm – the theory of self-organization in open non-equilibrium ...
Malуarets Lyudmyla M.   +3 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The supply side of innovation diffusion - A UK SME broadband adoption perspective [PDF]

open access: yes, 2011
Recent research suggests that the majority of the Small and medium sized enterprises (SMEs) e-business research focusses primarily on studying innovation diffusion within the SMEs themselves with limited research into the supply-side of innovation ...
Oni, O, Papazafeiropoulou, A
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Innovation Toilet and Barriers of Diffusion in Developing Country Case Study: TOTO Electronic Bidet Seat Toilet

open access: yesAsian Journal of Technology Management, 2012
The innovation of electronic bidet seat toilet in Japan has diffused to more than sixty percent of Japanese household while it has low rate of diffusion in other countries especially in developing country.
Akbar Adhiutama   +2 more
doaj   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

The contribution of teamwork, thinking styles, and innovation towards knowledge management [PDF]

open access: yes, 2009
Knowledge management can be enhanced by creating conditions that facilitate knowledge creation, thus the concepts of teamwork,thinking styles, and innovation are central to the effective utilisationof knowledge.
Ratnasingam, Malini
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

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