Results 41 to 50 of about 273,156 (307)

Genetics and environmental determinants of Alzheimer’s disease and related dementias in older Africans: a narrative review

Genes and Environment
The burden of Alzheimer’s disease and related dementias (ADRD) is rising in Africa, yet research remains limited compared to high-income regions. This narrative review investigated the genetic and environmental determinants of ADRD in older African ...
Tobi Olajide, Oluwatimilehin Oladapo, Chukwuebuka Asogwa, Gideon Olajide, Ayomide Oyekan, Ayomide Fatola, Timileyin Olanrewaju, Damola Oyegbile, Ikechukwu Ugbo, Henry Oyoyo, Ridwan Kamarudeen, Olawale Famakin   +11 more
doaj   +1 more source

Toxic Alexandrium Treatment in Western Australia: Investigating the Efficacy of Modified Nano Clay

Toxins
Alexandrium spp. blooms produce a range of toxins, including spirolides, goniodomins, and paralytic shellfish toxins (PSTs). Of these, PSTs are the most impactful due to their high affinity for voltage-gated sodium ion channels in nerve cell membranes ...
Cherono Sheilah Kwambai, Houda Ennaceri, Alan J. Lymbery, Damian W. Laird, Jeff Cosgrove, Navid Reza Moheimani   +5 more
doaj   +1 more source

What Attracts People to the Life Sciences Industry, and What Motivates Them to Stay? [PDF]

, 2015
Life Sciences is seen as a hub for innovation and an industry that is working to improve the world by creating products to eradicate major diseases and improve the lives of people.
Subramanian, Vivek K
core   +2 more sources

Intercompartmental communication in senescence

FEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz, Eleanor J. Wind, Jixiang Leng, Myriam Gorospe   +3 more
wiley   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

A role for Biofoundries in rapid development and validation of automated SARS-CoV-2 clinical diagnostics

Nature Communications, 2020
The SARS-CoV-2 pandemic has created large demand on global testing capability. Here the authors use the London Biofoundry, an automated synthetic biology platform, and develop an open-source virus-like particle to implement high-throughput diagnostics.
Michael A. Crone, Miles Priestman, Marta Ciechonska, Kirsten Jensen, David J. Sharp, Arthi Anand, Paul Randell, Marko Storch, Paul S. Freemont   +8 more
doaj   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

London Creative and Digital Fusion [PDF]

, 2014
date-added: 2015-03-24 04:16:59 +0000 date-modified: 2015-03-24 04:16:59 +0000date-added: 2015-03-24 04:16:59 +0000 date-modified: 2015-03-24 04:16:59 +0000The London Creative and Digital Fusion programme of interactive, tailored and in-depth support was
Bolfek-Radovani, J, Briscoe, G, Dima, M, Fogg, H, Garner, C, Riedel, J, Shiach, M, Ternouth, P, Virani, T   +8 more
core  

Prevalence of Systemic Lupus Erythematosus in Australia, 2010–2022: A Population‐Based Study Using Linked National Administrative Health Data

Arthritis Care &Research, EarlyView.
Objective Systemic lupus erythematosus (SLE) is a heterogenous inflammatory condition with widely varying global prevalence estimates. The frequency of SLE in the general population of Australia has been reported to be notably lower than contemporary estimates in countries such as the United States or United Kingdom, at 19 to 39 per 100,000 as opposed ...
Lucinda Roper, Rachel Black, Joanna Tieu, Winnie Chen, Matthew Parker, Catherine Hill, Natasha Nassar, Mandana Nikpour   +7 more
wiley   +1 more source

Understanding the Impact of Assistive Technology on Users’ Lives in England: A Capability Approach

Bioengineering
This study presents an analysis of England’s 2023 national assessment of assistive technology (AT) access and use, with a particular focus on the qualitative impact of AT as described by users.
Rebecca Joskow, Dilisha Patel, Anna Landre, Kate Mattick, Catherine Holloway, Jamie Danemayer, Victoria Austin   +6 more
doaj   +1 more source