Results 51 to 60 of about 2,380,562 (304)

INNOVATIVE WAY OF DEVELOPMENTAS A MECHANISM OF NATIONAL ECONOMY MODERNIZATION

RUDN Journal of Public Administration, 2017
In this article the authors discuss the importance of innovation in national development, stands out a chain and effect relationship between the development of innovative and natural improvement of quality of production.
Svetlana A Pervoykina, Denis N Putimtsev
doaj   +1 more source

Feasibility and Preliminary Efficacy of Integrative Neuromuscular Training for Childhood Cancer Survivors: A Pilot Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of childhood acute lymphoblastic leukemia (ALL) often exhibit early deficits in muscle and movement competence, which can compromise long‐term health. Integrative neuromuscular training (INT), a multifaceted approach combining fundamental movement activities with strength exercises, may help address these deficits during ...
Anna Maria Markarian, Robert U. Newton, Dennis R. Taaffe, Nicholas G. Gottardo, Santosh Valvi, Carolyn J. Peddle‐McIntyre, Jodie Cochrane Wilkie, Daniel A. Galvão   +7 more
wiley   +1 more source

The relationship between knowledge management and innovation level in Mexican SMEs: Empirical evidence [PDF]

, 2012
The transformation of the current society from an industry-based economy to a knowledge management and innovation-based economy is changing the design and implementation of business strategies and the nature of the competition among the organizations ...
García Pérez de Lema, Domingo, Maldonado Guzmán, Gonzalo, Martínez Serna, María del Carmen   +2 more
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

AI-driven innovation within the ICT sector

Smart Cities and Regional Development Journal
Innovation is pivotal in the competitive landscape of the Information and Communication Technology (ICT) sector, particularly in the context of rapidly evolving technological advancements.
Erika GRABOCKA, Ervisa NDOKA
doaj   +1 more source

Driving Innovation Initiatives in a Multinational Company Subsidiary: A Case Study and Conceptual Framework for Further Application

Journal of Open Innovation: Technology, Market and Complexity, 2022
: This study aims at identifying factors that facilitate the development of the capacity to generate innovations in a subsidiary of a multinational company.
Jeferson Lima Ribeiro, José Antônio Valle Antunes Junior, Débora Oliveira da Silva, Wagner Dorneles da Silva, Miguel Afonso Sellitto   +4 more
doaj   +1 more source

Human Resource Management And The Performance Of Selected Small And Medium Manufacturing Enterprises [PDF]

, 2012
Despite many studies on human resource management can be found in the literature, until recently, studies on the moderating effects of this factor on the relationship between innovation and firm performance are hardly existent.
M. Mohd , Rosli, Rosman , Mahmood
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Towards Smart Public Administration: A TOE-Based Empirical Study of AI Chatbot Adoption in a Transitioning Government Context

Administrative Sciences
As governments pursue digital transformation to improve service delivery and administrative efficiency, AI chatbots have emerged as a promising innovation in smart public administration.
Mansur Samadovich Omonov, Yonghan Ahn
doaj   +1 more source