Results 101 to 110 of about 603,389 (312)
Innovation and business performance - a provisional multi-regional analysis [PDF]
Although much attention has focussed on the determinants of firms' innovation performance, the relationship between innovation and business performance is less well defined.
Smallbone, David +4 more
core
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Innovation Project Performance Measurement: Selected Shortcomings
Littera Scripta, 2015 This paper presents an overview of studies that describe the emergence of innovation project performance measurement. It is dedicated to the issue of economic indicators and focuses on the metrics that can be employed to evaluate a single innovation ...
Ondřej Žižlavský
doaj
MetalsBody-centered cubic (BCC) metals, extensively utilized in low-alloy high-strength steels and heat-resistant alloys, exhibit a pronounced ductile–brittle transition (DBT) at cryogenic temperatures, marked by a well-defined yet narrow ductile–brittle ...
Jie Zhang +4 more
doaj +1 more source
Impact of strategy, HRM Strength and HRM bundles on innovation performance and organizational performance [PDF]
This study uses structural equation modeling to test a model of the impact of human resource management bundles on perceived organizational performance and innovation performance, on a large sample of companies.
Cunha, Miguel Pina e +1 more
core
Innovation Capability and Organisational Performance [PDF]
, 2019 Innovation is crucial for businesses to address key challenges anticipated by the changes in socioeconomic and environmental issues. Innovation capability is largely seen as a vital source for generating sustainable competitive advantage.
Al-Kalouti, J., Kumar, V., Kumar, N., Garza-Reyes, J.A., Upadhyay, A., Zwiegelaar, J.B., Kumari, A.
core
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
What do we really know about when technological innovation improves performance (and when it does not)? [PDF]
Most approaches to innovation bear the implicit assumption that increased innovativeness leads to improved organizational performance. Thus, more attention has been focused on innovativeness than on innovation performance; on novelty than on value ...
Adegbesan, Tunji, Ricart, Joan E.
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source