Results 51 to 60 of about 23,707,889 (338)
The Financial Performance of an Innovative Megaproject
Procedia - Social and Behavioral Sciences, 2014 The financial structure of megaprojects, known in the literature as project finance, is characterized by the creation of a legally independent project company financed with a concentrated equity ownership and a high level of non-recourse debt. Research in this field may yield new ideas and theories about the existing theoretical framework on capital ...
Irimia Diéguez, Ana Isabel +2 more
openaire +4 more sources
Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin +17 more
wiley +1 more source
MetalsThis study evaluates the tribological characteristics of quasi-monolithic engine cylinder coatings and piston rings using a custom-built linear reciprocating tribometer.
Siddharth Banerjee +3 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Human Behavior and Emerging TechnologiesDemographic aging presents new challenges and highlights the growing need for smart healthcare applications tailored to older adults. This paper presents the assessment of a mobile health application designed to facilitate the communication between ...
Agnese Augello +5 more
doaj +1 more source
International Journal of Strength and ConditioningGolf swing performance has been found to be influenced by health status, physical fitness, and technical abilities. However, as the sport becomes more competitive, athletes and coaches regularly seek novel approaches to optimizing athletic performance ...
Quincy Johnson +7 more
doaj +1 more source
The Effect of Proximity on Enterprise Innovation Performance in the Innovation Ecosystem
IEEE Access, 2023 The establishment and improvement of an innovation ecosystem have become important issues in building an innovative powerhouse. Built on the background of innovation ecosystem, from the perspective of cooperative interaction and dynamics, this study introduces value co-creation and dynamic capabilities, and analyzes how the proximity between ...
Yan Zhao, Yan Xiao, Jianlin Lyu
openaire +3 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Innovation and venture capital exit performance [PDF]
, 2011 Venture capital is a potent source of R&D financing which contributes significantly to technological innovation output in the form of patented inventions.
Pierre Nadeau, Nadeau, Pierre
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source