Results 61 to 70 of about 603,389 (312)
, 2023 This study develops a conceptual model to examine the effect of nonfinancial performance measures on absorptive capacity, organizational learning, and innovation performance.
Sands, John +7 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
THE RELATIONSHIP OF INNOVATION WITH ORGANIZATIONAL PERFORMANCE
International Journal of Research -GRANTHAALAYAH, 2017 This research study investigates the relationship of innovation with organizational performance of the telecommunication sector. The independent variables are process innovation, product innovation and organizational innovation as an organizational culture as moderating variable. The research is survey research in which questionnaire is administered to
Abdul karim Suhag +4 more
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
npj Computational Materials, 2023 Existing hot sintering models based on molecular dynamics focus on single-crystal alloys. This work proposes a new multiparticle model based on molecular dynamics to investigate coalescence kinetics during the hot-pressed sintering of a polycrystalline ...
Qingwei Guo +5 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Alliance Portfolios and Innovation Performance
Group & Organization Management, 2012 Whereas existing alliance portfolio studies mainly focus on the structure or management of alliance portfolios, we conceptually explore the connections between them. In particular, we formulate propositions, arguing that the formalization, centralization, and customization of alliance portfolio management moderate the relationship between the ...
Faems, D.L.M., Janssens, M., Neyens, I.
openaire +2 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Journal of Research in Education Sciences韓國早期之高齡政策係以「活力老化」（active ageing）為核心理念，強調透過經濟保障、健康促進與休閒文化建構等措施，提升退休老人之生活品質。然而，面對少子化情況加劇，以及人口快速老化與科技發展所引發之社會結構變遷，傳統高齡政策在回應高齡族群日益多元的需求與生活品質提升方面已顯不足。為回應此一轉變，韓國政府設立「首爾50Plus財團」（Seoul 50 Plus Foundation），並推動「50Plus政策」，致力於強化中老年職涯規劃、再就業能 力與社會參與等方面的支持機制 ...
朴東飛 Dong-Bee Park
doaj +1 more source