Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Administrative SciencesDespite growing interest in organizational well-being, digitalization, and collaboration, their interrelations remain insufficiently explored in the context of small enterprises.
Jelke Roorde Veltman +1 more
doaj +1 more source
Measuring the Enterprise Green Innovation Strategy Decision-Making Quality: A Moderating-Mediating Model. [PDF]
Front Psychol, 2022 Feng J, Pan Y, Zhuang W.
europepmc +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Impact of Environmental Innovation Strategy on Green Competitiveness: Evidence from China. [PDF]
Int J Environ Res Public Health, 2022 Wang N, Zhang SJ, Wang W.
europepmc +1 more source
Interfirms Collaboration - the Basis for Interorganizational Innovation [PDF]
In the current economic environment, interfirm collaboration for innovation is increasingly present because of the opportunities for growth and development that it offers to the partners involved and it is included in the company’s strategy, designed ...
Raluca ZOLTAN
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
How Does Sustainable Leadership Affect Environmental Innovation Strategy Adoption? The Mediating Role of Environmental Identity. [PDF]
Int J Environ Res Public Health, 2023 Hu L, Chang TW, Lee YS, Yen SJ, Ting CW.
europepmc +1 more source
Complementarity between technology make and buy in innovation strategies: evidence from Belgian manufacturing firms. [PDF]
This paper characterizes the innovation strategy of manufacturing fims and examines the relation between the innovation strategy and important industry-, firm- and innovation-specific characteristics using Belgian data from the Eurostat Community ...
Cassiman, Bruno, Veugelers, Reinhilde
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source