Results 81 to 90 of about 438,479 (266)

Impact of Environmental Innovation Strategy on Green Competitiveness: Evidence from China. [PDF]

Int J Environ Res Public Health, 2022
Wang N, Zhang SJ, Wang W.
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

How Does Sustainable Leadership Affect Environmental Innovation Strategy Adoption? The Mediating Role of Environmental Identity. [PDF]

Int J Environ Res Public Health, 2023
Hu L, Chang TW, Lee YS, Yen SJ, Ting CW.
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

stBERT: A Pretrained Model for Spatial Domain Identification of Spatial Transcriptomics

IEEE Access
Recent studies have shown that clustering latent variables, derived from autoencoders (AEs) through reconstruction tasks, is effective for identifying spatial domains of spatial transcriptomics (ST).
Ziheng Wang, Xinhe Li, Hiroaki Takada, Ryoichi Nagatomi   +3 more
doaj   +1 more source

Bridging the knowledge gap between technology and business: An innovation strategy perspective. [PDF]

PLoS One, 2022
Peykani P, Namazi M, Mohammadi E.
europepmc   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Obtaining interactions among science, technology, and research policy for developing an innovation strategy: A case study of supercapacitors. [PDF]

Heliyon, 2022
Ishii C, Asatani K, Sakata I.
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Digitalization and Organizational Climate for Well-Being in Small European Firms: Does Collaboration Matter?

Administrative Sciences
Despite growing interest in organizational well-being, digitalization, and collaboration, their interrelations remain insufficiently explored in the context of small enterprises.
Jelke Roorde Veltman, Inna Majoor-Kozlinska   +1 more
doaj   +1 more source