Results 71 to 80 of about 9,827,909 (347)

Effect of green innovation strategy on firm‐idiosyncratic risk: A competitive action perspective

Business Strategy and the Environment, 2019
Despite increasing concern for corporate environmental responsibility in numerous industries, the relationship between green innovation strategy (GIS) and idiosyncratic risk is a rarely scrutinised topic, particularly in the automotive domain.
Woon Leong Lin, A. Mohamed, M. Sambasivan, N. Yip   +3 more
semanticscholar   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

EU Cohesion Policy: A suitable tool to foster regional innovation? Bertelsmann Policy Paper, 2019 [PDF]

, 2019
Across Europe, regions are divided into innovation leaders and moderate innovators – the latter referring to regions that lag behind in terms of prosperity and R&D activities.
Schmidt, Juliane
core  

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Do product innovation-related activities affect downsizing decisions? An organizational efficiency perspective [PDF]

, 2017
Firms’ innovation strategy typically involves the need to shape organizational changes within work structures and routines, even those concerning employee downsizing decisions.
Estrella Ramón, Antonia, Jiménez Castillo, David, Magán Díaz, Amalia, Rondán Cataluña, Francisco Javier (Coordinador)   +3 more
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Economic Inequalities in Immunization Coverage Among One-Year-Olds and Coverage Gains from Closing the Inequality Gap in 10 Low- and Middle-Income Countries in the Western Pacific Region, 1994–2021

Vaccines
Background: Immunization coverage has increased substantially in the Western Pacific Region, saving millions of lives and supporting disease elimination efforts.
Ana Mendez-Lopez, Roland Dilipkumar Hensman, Shanlong Ding, Kidong Park   +3 more
doaj   +1 more source

China's absorptive State: research, innovation and the prospects for China-UK collaboration [PDF]

, 2013
China's innovation system is advancing so rapidly in multiple directions that the UK needs to develop a more ambitious and tailored strategy, able to maximise opportunities and minimise risks across the diversity of its innovation links to China. For the
Adams, Jonathan, Bound, KIrsten, Saunders, Tom, Wilsdon, James   +3 more
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

I Like The Way You Move: An Empirical Investigation into the Mechanisms Behind First Mover and Follower Strategies [PDF]

There appears to be an ambivalent dimension in innovation strategies: timing. When is an innovation ready for the market or when is the market ready for the innovation? This paper empirically investigates the determinants of a firm?s decision to become a
Schmidt, Tobias, Sofka, Wolfgang
core   +3 more sources