Results 41 to 50 of about 11,103,293 (250)

Protein Polarimetry, Perfected: Specific Rotation Measurement for the Refracto-Polarimetric Detection of Cryptic Protein Denaturation

Biophysica
Protein polarimetry has been evaluated as a simple and straightforward technique to detect the cryptic denaturation of exemplary proteins. The general rules of rotation vs.
Lisa Riedlsperger, Heinz Anderle, Andreas Schwaighofer, Martin Lemmerer   +3 more
doaj   +1 more source

Explorando Distintos Tipos de Innovación en Micro y Pequeñas Empresas Peruanas

Journal of Technology Management & Innovation, 2013
This article explores the innovation phenomenon, from a multidimensional perspective, in two groups of micro and small enterprises of traditional sectors.
José Isaac Yrigoyen
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Enhancing the Energy Efficiency of a Proton Exchange Membrane Fuel Cell with a Dead-Ended Anode Using a Buffer Tank

Energies
Enhancing energy efficiency is essential for proton exchange membrane fuel cells (PEMFCs) operating in a dead-ended anode (DEA) mode. This study proposes the integration of a buffer tank, positioned between the mass flow meter and the fuel cell, to ...
Trung-Huong Tran, Karthik Kannan, Amornchai Arpornwichanop, Yong-Song Chen   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Notes on interdiction in the Civil Procedure Code of 2015 (part 1)

Revista Eletrônica de Direito Processual, 2015
This study covers the procedure for interdiction of persons (declaration of mental or physical incapacity) under the Civil Procedure Code of 2015, highlighting its main innovations.
Leonardo Faria Schenk
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

ANALYSIS OF TECHNOLOGICAL INNOVATIONS MANAGEMENT AT RUSSIAN INDUSTRIAL ENTERPRISES: SOURCES OF FINANCING, INNOVATIVE STRATEGY

Russian Journal of Economics and Law, 2012
The article analyzes technological innovations management at Russian industrial enterprises, basing on the study of financial sources of the innovative-technological activity of industrial enterprises, determining the type of innovative strategy of ...
G. I. Gumerova, E. Sh. Shaimiyeva
doaj   +2 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

THE IMPACT OF PRODUCT AND PROCESS INNOVATIONS ON FINANCIAL RESULTS: АN EMPIRICAL STUDY OF RUSSIAN COMPANIES

Стратегические решения и риск-менеджмент
The relationship between product and process innovation and financial performance remains largely unexplored, especially for Russian firms. An analysis of publications on this topic shows both a positive and a negative relationship.
O. M. Orlovtseva, E. V. Gubanova
doaj   +1 more source