Results 91 to 100 of about 2,717,339 (281)

New quality of financial institutions and business management [PDF]

open access: yes, 2020
Economic processes in the world are characterized by a high level of dynamism, change and innovative approaches to addressing key issues in nowadays.
Kraus, Kateryna   +2 more
core  

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Інноваційні резерви підвищення продуктивності інтелектуальної праці в Україні

open access: yes, 2013
The major macroeconomic influencing factors on development country effectiveness by innovative model have been determined in the article. By analyzing the supporting of development country by innovative model regulatory framework the weaknesses and ...
Nevdakha, Оlga, Невдаха, О. Ю.
core  

SUSTAINABLE DEVELOPMENT OF TERRITORIES OF MINING REGIONS [PDF]

open access: yes, 2018
Developing innovative technologies of mining coal seams and increasing the competitiveness of coal produced and providing further diversification of the mine using the "post-mining" concept as the basis for sustainable ...
DUBOVIK, Oleksandr, LOHUNOVA, Oleksandra
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Methodological aspects of implementing an innovative approach to improving the efficiency of development projects

open access: yesНедвижимость: экономика, управление
In this paper, the authors touch upon the issue of competition of development companies and the existing trends of increasing the competitiveness of development projects in modern conditions. There are two main approaches to increasing competitiveness.
Aleksei Vyacheslavovich Mokaseev   +2 more
doaj   +1 more source

Managing Innovations in Higher Education [PDF]

open access: yes
Discussed in the article is the concept of «technopark» ideology in regional development. The article describes how this ideology is implemented in consumer co-operatives institutions of higher education, dwells on their innovative strategies, best ...
Marina V. KHAYRULLINA
core  

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

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