Results 91 to 100 of about 2,717,339 (281)
New quality of financial institutions and business management [PDF]
Economic processes in the world are characterized by a high level of dynamism, change and innovative approaches to addressing key issues in nowadays.
Kraus, Kateryna +2 more
core
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Інноваційні резерви підвищення продуктивності інтелектуальної праці в Україні
The major macroeconomic influencing factors on development country effectiveness by innovative model have been determined in the article. By analyzing the supporting of development country by innovative model regulatory framework the weaknesses and ...
Nevdakha, Оlga, Невдаха, О. Ю.
core
SUSTAINABLE DEVELOPMENT OF TERRITORIES OF MINING REGIONS [PDF]
Developing innovative technologies of mining coal seams and increasing the competitiveness of coal produced and providing further diversification of the mine using the "post-mining" concept as the basis for sustainable ...
DUBOVIK, Oleksandr, LOHUNOVA, Oleksandra
core
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
In this paper, the authors touch upon the issue of competition of development companies and the existing trends of increasing the competitiveness of development projects in modern conditions. There are two main approaches to increasing competitiveness.
Aleksei Vyacheslavovich Mokaseev +2 more
doaj +1 more source
Managing Innovations in Higher Education [PDF]
Discussed in the article is the concept of «technopark» ideology in regional development. The article describes how this ideology is implemented in consumer co-operatives institutions of higher education, dwells on their innovative strategies, best ...
Marina V. KHAYRULLINA
core
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source

