Results 91 to 100 of about 18,999,904 (305)

IDB Newsletter: Vol. 7, no. 2, April 1969

, 1969
IDB Newsletter is a monthly publication of the Inter-American Development that reports on the activities of the Inter-American Development Bank and appears in English and Spanish ...
Inter-American Development Bank
core   +1 more source

Recent advances in triple negative breast cancer: the immunotherapy era

BMC Medicine, 2019
Background Several accomplishments have been achieved in triple-negative breast cancer (TNBC) research over the last year. The phase III IMpassion130 trial comparing chemotherapy plus atezolizumab versus chemotherapy plus placebo brought breast cancer ...
Antonio Marra, Giulia Viale, Giuseppe Curigliano   +2 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

IDB Newsletter: Vol. 8, no. 3, July 1970

, 1970
IDB Newsletter is a monthly publication of the Inter-American Development that reports on the activities of the Inter-American Development Bank and appears in English and Spanish ...
Inter-American Development Bank
core   +1 more source

STATE AND DIRECTIONS OF INNOVATIVE DEVELOPMENT OF INDUSTRY IN RUSSIA

Russian Journal of Economics and Law, 2012
The article analyzes the dynamics of the main indicators of the innovative development of the Russian industry in interconnection with the main provisions of strategy of innovative development of Russia till 2020.
E. A. Tretyakova
doaj  

The transcriptome analysis reveals the regulatory mechanisms of female sterility in Lagerstroemia speciosa ‘Zichan’

BMC Plant Biology
Background Ovule abortion presents a major biological obstacle to hybrid breeding in the genus Lagerstroemia, but its molecular regulatory mechanisms remain inadequately understood.
Ruoyong Yin, Shuaijie Lu, Baojin Zhang, Fei Xiao, Lan Wang, Ruchun Xi, Xiaomei Deng   +6 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Comparative transcriptomic analysis of petaloid stamen formation in Lagerstroemia speciosa ‘Zijuan’

BMC Genomics
Background Lagerstroemia speciosa ‘Zijuan’ is a new variety of L. speciosa with highly petaloid stamens that exhibit ornamental value but sterility. To investigate the mechanism of stamen petaloidy, this study compared the morphological structures and ...
Baojin Zhang, Ruoyong Yin, Shuaijie Lu, Lan Wang, Fei Xiao, Ruchun Xi, Xiaomei Deng   +6 more
doaj   +1 more source

Assessing essential oil composition in Cinnamomum cassia leaves from different regions of China using GC-MS and FTIR spectroscopy

Czech Journal of Food Sciences
In this study, volatile compounds from Cinnamomum cassia Presl. leaves from different regions of China were identified using gas chromatography coupled with mass spectrometry (GC-MS) and Fourier-transform infrared (FTIR) spectroscopy combined with ...
Yan Huang, Yujie Liu, Huiping Tan, Yanrong Cheng, Kunyang Tao, Dingze Gu, Huaizu Cai, Chengjie Li, Kaiyi Guo, Cheng Wu, Hong Wu, Yanqun Li   +11 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source