Results 131 to 140 of about 820,234 (313)

CAD Model Reconstruction by Generative Design of an iQFoil Olympic Class Foiling Windsurfing Wing

open access: yesJournal of Marine Science and Engineering
This work presents a generative design algorithm for the semi-automatic reconstruction of sweepable surfaces from point clouds obtained through three-dimensional scanning.
Antonino Cirello   +3 more
doaj   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Landscape of Innovative Methods for Early Diagnosis of Gastric Cancer: A Systematic Review. [PDF]

open access: yesDiagnostics (Basel), 2023
Orășeanu A   +7 more
europepmc   +1 more source

Management characteristics, collaboration and innovative efficiency: evidence from UK survey data [PDF]

open access: yes
This paper explores the impact of management characteristics and patterns of collaboration on a firmÕs innovation performance in transforming innovation resources into commercially successful outputs.
Andy Cosh, Alan Hughes, Xiaolan Fu
core  

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

A scoping review on innovative methods for personality observation. [PDF]

open access: yesFront Psychol, 2023
Mosca LL   +11 more
europepmc   +1 more source

Spatial embeddedness and firm performance: an empirical exploration of the effects of proximity on innovative and economic performance [PDF]

open access: yes
Recent theoretical developments in organisation science and regional economics have emphasised the importance of networks and geographical proximity for the performance of firms.
Oerlemans, Leon A.G., Meeus, Marius T.H.
core  

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Comprehensive Understanding of Hispanic Caregivers: Focus on Innovative Methods and Validations. [PDF]

open access: yesJ Alzheimers Dis Rep, 2023
Sehar U   +8 more
europepmc   +1 more source

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