Results 141 to 150 of about 820,234 (313)

Innovations in Qualitative Methods

, 2017
In this chapter, we explore four particular ways in which innovation has pushed qualitative data collection beyond the familiar focus on face-to-face interviews. We have chosen these methods both for their practicality and because they are tools and techniques we have used ourselves; as committed qualitative researchers, we can attest to their value ...
Virginia Braun, Victoria Clarke, Debra Gray   +2 more
openaire   +1 more source

Anchoring qualitative methods for longitudinal studies

, 2016
This chapter details an innovative research methods approach to measuring change in experiences at work over multiple time periods and worksites. Using a recent research project in a large public sector organisation we describe a longitudinal study where
Townsend, Keith, Loudoun, Rebecca
core   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

A Video Repository for Innovative Methods of Dietary Assessment and Analysis. [PDF]

J Vis Exp, 2023
Bromage S, Fung TT, Kirkpatrick SI, Willett WC.   +3 more
europepmc   +1 more source

Changing Perceptions of Knowledge: Evaluation Of An Innovative Program For Pre-Service Secondary Teachers

, 2005
Pre-service programs for secondary teachers have traditionally involved method subjects, where participants are inducted into the curriculum practices of two disciplinary or subject areas. In 2003, Victoria University of Technology, Melbourne, enrolled a
Moore, Rod, Hooley, Neil
core   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Current Innovative Methods of Fetal pH Monitoring-A Brief Review. [PDF]

Diagnostics (Basel), 2022
Bohiltea RE, Mihai BM, Ducu I, Cioca AM, Bohiltea AT, Iordache AM, Iordache SM, Grigorescu CEA, Marinescu S.   +8 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Basket trials in oncology: a systematic review of practices and methods, comparative analysis of innovative methods, and an appraisal of a missed opportunity. [PDF]

Front Oncol, 2023
Kasim A, Bean N, Hendriksen SJ, Chen TT, Zhou H, Psioda MA.   +5 more
europepmc   +1 more source